Hormones and the Brain

  • Kordon Claude 
  • Gaillard Rolf-Christian 
  • Christen Yves 
Part of the Research and Perspectives in Endocrine Interactions book series (RPEI)

Table of contents

  1. Front Matter
    Pages I-XVII
  2. Peter C. Gray, Louise M. Bilezikjian, Craig A. Harrison, Ezra Wiater, Wylie Vale
    Pages 1-28
  3. Dorret Boomsma, Gonneke Willemsen, Eco de Geus, Nina Kupper, Danielle Posthuma, Richard IJzerman et al.
    Pages 29-46
  4. Sergio R. Ojeda, Alejandro Lomniczi, Alison Mungenast, Claudio Mastronardi, Anne-Simone Parent, Christian Roth et al.
    Pages 47-60
  5. Joe I, Kipp J L, Ramirez V D
    Pages 61-72
  6. H. Vaudry, J.L. Do Rego, D. Beaujean-Burel, J. Leprince, L. Galas, D. Larhammar et al.
    Pages 99-109
  7. M. Schumacher, A. Ghoumari, R. Guennoun, F. Labombarda, S.L. Gonzalez, M.C. Gonzalez Deniselle et al.
    Pages 111-154
  8. J. Balthazart, M. Baillien, C.A. Cornil, T.D. Charlier, H.C. Evrard, G.F. Ball
    Pages 173-199
  9. Caleb E. Finch, Todd Morgan, Irina Rozovsky
    Pages 213-225
  10. Marianne B. Müller, Florian Holsboer
    Pages 227-236
  11. Back Matter
    Pages 237-238

About these proceedings

Introduction

Peripheral hormones have a major impact on the brain: they are able to interfere with its development, to affect release of neurotransmitters and concentrations of receptors, to trigger growth factors involved in lesion repair. These multiple actions account for their capacity to modulate a number of physiological parameters, from reproductive functions to memory, behaviour and aging. Depending upon intensity and duration of exposure, they can be either neuroprotective or neurotoxic, for instance by affecting production of free radicals. This book, based on contributions of pioneer investigators in the field, outlines the ambiguous actions of gonadal steroids (estradiol, progesterone, testosterone, inhibin and activin) and of neurosteroids, related moieties produced in the brain itself. After summarizing their multiple mechanisms of action, which involve both direct effects on neuronal membranes and activation of genes coding for specific proteins in neurons or glial cells, the book outlines the role of hormones in pathogenic processes such as mental disturbances or neurodegenerative diseases.

Keywords

Antiprogestins Aromatase Activity Corticotropin-Releasing Horrmone Endogenous Neuroprotection Hypothalamic Nerve Cells Nervous System Neurosteroids Progestins estrogen receptor growth factor neuropeptides puberty steroids

Editors and affiliations

  • Kordon Claude 
    • 1
  • Gaillard Rolf-Christian 
    • 2
  • Christen Yves 
    • 3
  1. 1.Institut NeckerParisFrance
  2. 2.Dept. Medecine Interne, Div. EndocrinologieCentre Hospitaier Universitaire VadoisLausanneSwitzerland
  3. 3.Fondation IPSENPour la Recherche ThérapeutiqueParis Cedex 16France

Bibliographic information

  • DOI https://doi.org/10.1007/b138340
  • Copyright Information Springer-Verlag Berlin Heidelberg 2005
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-540-21355-0
  • Online ISBN 978-3-540-26940-3