Neuroblastoma

  • Nai-Kong V. Cheung
  • Susan L. Cohn

Part of the Pediatric Oncology book series (PEDIATRICO)

Table of contents

  1. Front Matter
    Pages I-XV
  2. Andrew F. Olshan
    Pages 1-5
  3. William G. Woods
    Pages 7-20
  4. John M. Maris, Garrett M. Brodeur
    Pages 21-26
  5. Manfred Schwab
    Pages 27-40
  6. Robert A. Ross
    Pages 55-61
  7. Frank Berthold, Thorsten Simon
    Pages 63-85
  8. Hiroyuki Shimada, Inge M. Ambros
    Pages 87-95
  9. Sara J. Abramson, Barry L. Shulkin
    Pages 109-122
  10. Brian H. Kushner, Susan L. Cohn, Katherine K. Matthay, Nai-Kong V. Cheung, Michael P. La Quaglia, Daphne A. Haas-Kogan et al.
    Pages 123-192
  11. Katherine K. Matthay, Brian H. Kushner
    Pages 193-211
  12. Kim Kramer, Michael R. Pranzatelli
    Pages 213-222
  13. Nai-Kong V. Cheung, Paul M. Sondel
    Pages 223-242
  14. Carol J. Thiele, C. Patrick Reynolds
    Pages 243-256
  15. Darrell J. Yamashiro, Susan L. Cohn
    Pages 257-265
  16. Jennifer K. Peterson, Peter J. Houghton
    Pages 267-276
  17. Caroline Laverdière, James Gurney, Charles A. Sklar
    Pages 277-288
  18. Nai-Kong V. Cheung, Susan L. Cohn
    Pages 289-291

About this book

Introduction

Neuroblastoma is a medical enigma. As a childhood neoplasm arising from neural crest cells, it is characterized by diverse clinical behaviors ranging from spontaneous remission to rapid tumor progression and death. Although clinical outcome can be predicted to a large extent by the stage of disease and the age at diagnosis, an in-depth understanding of its clinico-pathological behavior, now greatly aided by sophisticated molecular genetic profiling, will improve diagnostic precision and refine risk-based therapies. Comprehensive international efforts have advanced our understanding of tumor biology and improved the clinical management of children with neuroblastoma. This book reviews our current understanding of the genes and biological pathways that contribute to neuroblastoma pathogenesis, modern risk-based treatment approaches for these patients, and recent advances in biologically based therapy. It provides a concise up-to-date reference for practitioners, students, and researchers.

Keywords

Clinical trials Genetics Neuroblastoma Risk groups Therapeutics angiogenesis imaging

Editors and affiliations

  • Nai-Kong V. Cheung
    • 1
  • Susan L. Cohn
    • 2
    • 3
  1. 1.Department of PediatricsMemorial Sloan-Kettering Cancer CenterNew YorkUSA
  2. 2.Department of Pediatrics and the Comprehensive Robert H. Lurie Cancer CenterNorthwestern UniversityChicagoUSA
  3. 3.Feinberg School of MedicineChildren's Memorial HospitalChicagoUSA

Bibliographic information

  • DOI https://doi.org/10.1007/b137762
  • Copyright Information Springer-Verlag Berlin Heidelberg 2005
  • Publisher Name Springer, Berlin, Heidelberg
  • eBook Packages Medicine
  • Print ISBN 978-3-540-40841-3
  • Online ISBN 978-3-540-26616-7
  • Series Print ISSN 1613-5318
  • About this book