Table of contents

  1. Front Matter
    Pages I-XVII
  2. Clinkal Issues and Tissue Processing

    1. Christopher A. Moskaluk
      Pages 3-15
    2. Issac Yi Kim, David K. Ornstein
      Pages 17-26
    3. Gallya Gannot, John W. Gillespie
      Pages 27-42
    4. G. Steven Bova
      Pages 43-53
  3. Methods of Tissue Microanalysis

    1. Stephen M. Hewitt
      Pages 57-66
  4. Molecular Analysis of Microdissected Samples

    1. Michael A. Tangrea, John W. Gillespie, Michael J. Flaig, Gallya Gannot, Vladimir Knezevic, Michael R. Emmert-Buck et al.
      Pages 69-100
    2. Sergio Gonzáez
      Pages 101-110
    3. Pablo Uribe, Ignacio I. Wistuba
      Pages 111-123
    4. Fatih Ozsolak, Veronica Luzzi, Mark A. Watson
      Pages 125-144
    5. David H. Geho, Lance A. Liotta, Emanuel F. Petricoin
      Pages 145-162
  5. Back Matter
    Pages 221-224

About this book


The book provides an updated overview of molecular analysis of human tissues, and the impact this analysis has on diagnosis and prognosis of human diseases. Special emphasis is placed on human cancer and the future directions of the field. Methods of handling clinical tissue samples, including the impact of handling on subsequent molecular analysis, are also discussed. In addition, detailed protocols for molecular analysis of DNA, RNA and protein, with special emphasis on molecular analysis of highly complex human tissue samples containing mixtures of cell populations, are provided.


Analyse, molekulare DNA Gewebe, Präparierung, Sektion Nukleinsäuren Proteine RNA analysis, molecular microdissection nucleid acids proteins tissue

Editors and affiliations

  • Michael R. Emmert-Buck
    • 1
  • John W. Gillespie
    • 1
  • Rodrigo F. Chuaqui
    • 1
  1. 1.Pathogenetics Unit, Advanced Technology Center, Laboratory of Pathology and Urologic Oncology Branch, Center for Cancer ResearchNational Cancer InstituteBethesdaUSA

Bibliographic information