Bone Resorption

  • Felix Bronner
  • Mary C Farach-Carson
  • Janet Rubin

Part of the Topics in Bone Biology book series (TBB, volume 2)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Janet Rubin, Edward M. Greenfield
    Pages 1-23
  3. Merry Jo Oursler
    Pages 24-33
  4. Roland Baron, William C. Horne
    Pages 34-57
  5. Steven D. Bain, Ted S. Gross
    Pages 58-66
  6. Mark S. Nanes, Roberto Pacifici
    Pages 67-90
  7. Mark C. Horowitz, Melissa A. Kacena, Joseph A. Lorenzo
    Pages 91-107
  8. Lorraine A. Fitzpatrick
    Pages 128-150
  9. Gregory A. Clines, John M. Chirgwin, Theresa A. Guise
    Pages 151-174
  10. Back Matter
    Pages 175-189

About this book


Bone Resorption, the second volume in the series Topics in Bone Biology, deals with the osteoclast, the bone-resorbing cell, its origins, its enzymes, the regulation of osteoclast activity, and structural aspects of bone resorption. Diseases involving osteoclast function are discussed from the genetic viewpoint in two chapters that span transgenic mouse models to human pathology. Another chapter treats diseases of osteoclast function. Because osteoporosis may be considered a disease in which the bone resorption rate exceeds formation, a separate chapter deals with current and potential therapeutic approaches to this widespread disease that affects both men and women. Bone metastases and an analysis of the central role of the osteoclast in this condition are treated in the concluding chapter.

The reviews in the book are essential reading for clinicians, researchers and students in a variety of fields: skeletal biology and orthopedics, nutrition, rheumatology, endocrinology, nephrology, oncology, dentistry, nursing, and chiropractic medicine. Together with the earlier volume on Bone Formation, this volumes serves as a beacon to a field that has become a major topic for those who study the health concerns of the aged, the very young, athletes and those with cancer.


Bone resorption Cytokines Internist Osteoclasts bone complication nutrition pathophysiology physiology

Editors and affiliations

  • Felix Bronner
    • 1
    • 2
  • Mary C Farach-Carson
    • 3
  • Janet Rubin
    • 4
  1. 1.Department of BioStructure and FunctionUniversity of Connecticut Health CenterFarmingtonUSA
  2. 2.Department of PharmacologyUniversity of Connecticut Health CenterFarmingtonUSA
  3. 3.Department of BiologyUniversity of DelawareNewarkUSA
  4. 4.Division of Endocrinology and Metabolism, Emory University School of MedicineVeterans Affairs Medical CenterDecaturUSA

Bibliographic information