Hughes Syndrome

Antiphospholipid Syndrome

  • M. A. Khamashta

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Clinical Aspects

    1. Front Matter
      Pages 1-1
    2. M. A. Khamashta
      Pages 3-8
    3. Michelle Petri
      Pages 22-28
    4. Carlomaurizio Montecucco, Roberto Caporali
      Pages 29-40
    5. Josep Font, Ricard Cervera
      Pages 41-52
    6. Debendra Pattanaik, Robin L. Brey
      Pages 53-67
    7. Carlos A. Battagliotti
      Pages 86-98
    8. Mary-Carmen Amigo, Romeo García-Torres
      Pages 99-111
    9. Shirish R. Sangle, David P. D’Cruz
      Pages 112-116
    10. Jean-Charles Piette, Beverley J. Hunt
      Pages 117-126
    11. Maria G. Tektonidou, Haralampos M. Moutsopoulos
      Pages 127-139
    12. Elias Toubi, Aharon Kessel
      Pages 140-146
    13. Cristina Castañon, Pedro A. Reyes
      Pages 147-154
    14. Tonia L. Vincent, Charles G. Mackworth-Young
      Pages 155-170
    15. H. Michael Belmont
      Pages 171-180
    16. T. Flint Porter, Robert M. Silver, D. Ware Branch
      Pages 181-195
    17. Lisa R. Sammaritano
      Pages 196-208
    18. Lori B. Tucker, Rolando Cimaz
      Pages 241-257
    19. Wendell A. Wilson, Elena Cucurull
      Pages 258-263
    20. Beverley J. Hunt, Paul R. J. Ames
      Pages 264-271
  3. Laboratory Investigation

    1. Front Matter
      Pages 273-273
    2. Silvia S. Pierangeli
      Pages 275-290
    3. Jef M. M. C. Arnout, Jos Vermylen
      Pages 291-306
    4. Shinsuke Yasuda, Tatsuya Atsumi, Takao Koike
      Pages 307-318
    5. Maria Laura Bertolaccini
      Pages 319-328
  4. Basic Aspects

    1. Front Matter
      Pages 339-339
    2. Guillermina Girardi, Jane E. Salmon
      Pages 395-402
    3. Joan-Carles Reverter, Dolors Tàssies
      Pages 403-414
    4. Pier Luigi Meroni, Elena Raschi, Cinzia Testoni, Arianna Parisio, Maria Gerosa, Maria Orietta Borghi
      Pages 415-426
    5. Philip G. de Groot, Ronald H. W. M. Derksen
      Pages 427-438
    6. Chary López-Pedrera, Francisco Velasco, Maria J. Cuadrado
      Pages 439-445
    7. Jacob H. Rand, Xiao-Xuan Wu
      Pages 446-456
    8. Ian P. Giles, David A. Isenberg, Anisur Rahman
      Pages 470-491
    9. Keith B. Elkon, Neelufar Mozaffarian, Natalia Tishkevich
      Pages 492-500
    10. Eiji Matsuura, Kazuko Kobayashi, Luis R. Lopez
      Pages 501-520
    11. Tatsuya Atsumi, Olga Amengual
      Pages 521-531
    12. Silvia S. Pierangeli, Azzudin E. Gharavi
      Pages 532-543
  5. Therapy

    1. Front Matter
      Pages 545-545
    2. M. A. Khamashta, Guillermo Ruiz-Irastorza
      Pages 547-554
    3. Lorin Lakasing, Susan Bewley, Catherine Nelson-Piercy
      Pages 555-567
    4. Monica Galli, Tiziano Barbui
      Pages 568-578

About this book


The second edition of Hughes Syndrome: Antiphospholipid Syndrome addresses the complete range of conditions produced by this common disorder which is also known as APS or "sticky blood" syndrome. APS is one of the main causes of strokes (40%), leg deep vein thrombosis, and recurrent miscarriages in women. It is an important risk factor for thrombosis in women taking the oral contraceptive pill.

The effects of this syndrome were found initially in thrombosis, obstetrics (APS is the most common treatable cause of recurrent pregnancy loss) and neurology. Its impact is now felt in a diverse range of conditions. These include surgery (graft rejection), orthopedics (avascular necrosis, DVT), psychiatry (memory loss), cardiology (pulmonary hypertension, valvular disease, angina), ENT (vertigo), pediatrics (young strokes, epilepsy) to name but a few.

This new and updated text reflects the growth in published literature on APS and the widening ramifications of the disease. APS is a multi-specialty disease and is of increasing interest to obstetricians, rheumatologists, hematologists, dermatologists, neurologists and immunologists.


Antiphospholipid Syndrome Hughes Syndrome Sticky Blood Syndrome hypertension infertility neurology psychiatry transplantation

Editors and affiliations

  • M. A. Khamashta
    • 1
  1. 1.Lupus Research UnitSt Thomas’ HospitalLondonUK

Bibliographic information