Mitochondria and the Heart

  • José Marín-García

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 256)

About this book

Introduction

The function of the heart is highly dependent on oxidative energy that is generated in mitochondria. Defects in mitochondrial structure and function can be found in association with cardiovascular diseases. Mitochondria and the Heart discusses the role that mitochondria plays in cardiovascular disease, including biogenesis and function of cardiac mitochondria during normal growth, development and aging. In addition, nonbioenergetic, biogenesis and degradation pathways are explored. Understanding these pathways and the effects that mitochondrial defects have in cardiac pathology is extremely important in establishing the diagnosis and treatment of mitochondrial-based cardiac diseases.

José Marín-García is affiliated with The Molecular Cardiology and Neuromuscular Institute, Highland Park, New Jersey and the Department of Physiology & Biophysics, UMDNJ – Robert Wood Johnson Medical School, Piscataway, New Jersey.

 

Keywords

cardiology cardiovascular heart heart disease heart failure vascular disease

Editors and affiliations

  • José Marín-García
    • 1
    • 2
  1. 1.The Molecular Cardiology and Neuromuscular InstituteHighland Park
  2. 2.Department of Physiology & BiophysicsUMDNJ-Robert Wood Johnson Medical SchoolPiscataway

Bibliographic information

  • DOI https://doi.org/10.1007/b135603
  • Copyright Information Springer Science+Business Media, Inc. 2005
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine
  • Print ISBN 978-0-387-25574-3
  • Online ISBN 978-0-387-25575-0
  • Series Print ISSN 0166-9842
  • About this book