Estrogen Effects in Psychiatric Disorders

  • Niels Bergemann
  • Anita Riecher-Rössler

Table of contents

  1. Front Matter
    Pages I-X
  2. Anita Riecher-Rössler
    Pages 31-52
  3. Heinz Häfner
    Pages 53-94
  4. Robin Z. Hayeems, Mary V. Seeman
    Pages 95-106
  5. Niels Bergemann, Christoph Mundt, Peter Parzer, Benno Runnebaum, Franz Resch
    Pages 123-144
  6. Linda S. Kahn, Uriel Halbreich
    Pages 145-173
  7. Alain Gregoire
    Pages 191-206
  8. Gabriela Stoppe, Martina Dören
    Pages 207-222
  9. Tony Edwin, Uriel Halbreich
    Pages 223-237
  10. Peter Schönknecht, Johannes Pantel, Aoife Hunt, Marcus Henze, Thomas Strowitzki, Johannes Schröder
    Pages 253-270
  11. Khaled M.K. Ismail, G.V. Sunanda, P. M. Shaughn O'Brien
    Pages 271-287
  12. Back Matter
    Pages 289-291

About this book


A number of studies, mostly focusing on estrogen replacement therapy in women, have reported beneficial actions of these hormones on various neurobiological and neuropathological parameters in health and disease. Recent research has focused on gender differences and there is increasing evidence that estrogens exert protective effects in schizophrenia. Hormonal fluctuations or lack of estrogen may increase the risk of depression among vulnerable women. Treatment of depression with estrogen may stabilize and restore disrupted homeostasis – as during post-partum, premenstrual, or perimenopausal conditions – and act as a psychomodulator to offset vulnerability to dysphoric mood when estrogen levels are significantly decreased, as in the case of postmenopausal women. Studies on the effect of estrogens on Alzheimer’s Disease are still rather controversial, they do, however, facilitate the hypothesis that estrogens may have a modifying effect on the onset and course of AD, at least in subgroups of patients.


Alzheimer Depression Syndrom alzheimer's disease brain dementia hormone hormones pathophysiology physiology psychiatric disorder psychiatry schizophrenia therapy women

Editors and affiliations

  • Niels Bergemann
    • 1
  • Anita Riecher-Rössler
    • 2
  1. 1.Department of PsychiatryUniversity of HeidelbergGermany
  2. 2.Psychiatric Outpatient DepartmentUniversity of BaselSwitzerland

Bibliographic information

  • DOI
  • Copyright Information Springer-Verlag/Wien 2005
  • Publisher Name Springer, Vienna
  • eBook Packages Medicine
  • Print ISBN 978-3-211-40485-0
  • Online ISBN 978-3-211-27063-9
  • Buy this book on publisher's site