Biology of the Mammary Gland

  • Jan A. Mol
  • Roger A. Clegg

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 480)

Table of contents

  1. Front Matter
    Pages i-xiv
  2. Vera Fantl, Anna Creer, Christian Dillon, Janine Bresnick, David Jackson, Paul Edwards et al.
    Pages 1-7
  3. Catherin Niemann, 1,2Volker Brinkmann, Walter Birchmeier
    Pages 9-18
  4. Fred Sinowatz, Sabine Kölle, Dieter Schams, Annette Plath
    Pages 19-25
  5. Elizabeth Tonner, Gordon Allan, Lulzim Shkreta, John Webster, C. Bruce, A. Whitelaw et al.
    Pages 45-53
  6. Anastassia Hatzoglou, Efstathia Bakogeorgou, Marillena Kampa, Simone Panagiotou, Pierre-Marie Martin, Spyros Loukas et al.
    Pages 55-63
  7. Kirsty L. Bateman, Maryse Delehedde, Nicolas Sergeant, Isabelle Wartelle, Rishma Vidyasagar, David G. Fernig
    Pages 65-69
  8. Jan A. Mol, Irma Lantinga- van Leeuwen, Evert van Garderen, Ad Rijnberk
    Pages 71-76
  9. Charles V. Clevenger, Michael A. Rycyzyn
    Pages 77-84
  10. Nadine Binart, Christopher J. Ormandy, Paul A. Kelly
    Pages 85-92
  11. G. R. Cunha, J. F. Wiesen, Z. Werb, P. Young, Y. K. Hom, P. S. Cooke et al.
    Pages 93-97
  12. Roger A. Clegg, Rachel A. Gardner, Rushika N. Sumathipala, Françoise Lavialle, Raphaël Boisgard, Michéle Ollivier-Bousquet
    Pages 99-105
  13. Yvan de Launoit, Anne Chotteau-Lelievre, Claude Beaudoin, Laurent Coutte, Sonia Netzer, Carmen Brenner et al.
    Pages 107-116
  14. Rosemary Kane, Darren Finlay, Teresa Lamb, Finian Martin
    Pages 117-122
  15. Ross S. Thomas, Annie N.Y. Ng, Jiong Zhou, Martin J. Tymms, Wolfgang Doppler, Ismail Kola
    Pages 123-128
  16. Rachel S Chapman, Paula Lourenco, Elizabeth Tonner, David Flint, Stefan Selbert, Kyoshi Takeda et al.
    Pages 129-138
  17. C. Bruce A. Whitelaw
    Pages 147-153
  18. Claire Giamarchi, Catherine Chailleux, Hùløne Richard-Foy
    Pages 155-161

About this book

Introduction

Proceedings of the European Cooperation in the Field of Scientific and Technical Research (COST 825) Symposium on Mammary Gland Biology, held September 16-18, 1999, in Tours, France.
It is difficult to overstate the evolutionary and functional significance of mammary tissue in biology. Substantial progress has been made by researchers in various disciplines, particularly over the last fifteen years, towards realizing the potential of this tissue to yield powerful experimental models for morphogenesis and tissue development; for cellular differentiation; for the biosynthesis and secretion of proteins, lipids, small molecules and inorganic salts; and for the coordination and regulation of these processes. More recently, the possibility of exploiting the secretory epithelial cells of mammary tissue as `cell factories' has become a reality and the recombinant production by lactating animals of an increasing number of proteins, valuable both in the pharmaceutical and `nutraceutical' fields, is in progress or under development.
Also in this sphere of agricultural production, genetic as well as nutritional technologies are under investigation and exploitation to optimize milk composition for various end-uses - for instance in food process and manufacture. The possibilities of deriving health benefit from the bioactive properties of some of the minor constituents of milk are emerging to counter the highly-publicized negative health impact of excessive consumption of saturated animal fats. In human nutrition and medicine, the mammary gland is both a source of nutrition to the neonate and a potential health threat to the adult female - breast cancer remains the major single cause of female mortality in most developed countries.
This volume provides a unique glimpse into our understanding, at the cutting edge of a variety of disciplines, of this versatile and extraordinary tissue, at the birth of the twenty-first century.

Keywords

Mamma Tumor biology biosynthesis cell lines genes infections signal transduction

Editors and affiliations

  • Jan A. Mol
    • 1
  • Roger A. Clegg
    • 2
  1. 1.Utrecht UniversityUtrechtThe Netherlands
  2. 2.Hannah Research InstituteAyrScotland, UK

Bibliographic information

  • DOI https://doi.org/10.1007/b113398
  • Copyright Information Kluwer Academic Publishers 2002
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-0-306-46414-0
  • Online ISBN 978-0-306-46832-2
  • Series Print ISSN 0065-2598
  • About this book