Adrenomedullin in Cardiovascular Disease

  • Toshio┬áNishikimi

Part of the Basic Science for the Cardiologist book series (BASC, volume 19)

Table of contents

  1. Front Matter
    Pages i-x
  2. Kazuo Kitamura, Kenji Kangawa, Tanenao Eto
    Pages 1-16
  3. Takanobu Yoshimoto, Yukio Hirata
    Pages 17-40
  4. Toshihiko Ishimitsu, Kohju Tsukada, Junichi Minami, Hidehiko Ono, Hiroaki Matsuoka
    Pages 41-60
  5. Naoto Minamino
    Pages 61-82
  6. Takeshi Horio, Fumiki Yoshihara
    Pages 83-104
  7. Toshio Nishikimi
    Pages 105-129
  8. Johji Kato, Tanenao Eto
    Pages 131-154
  9. Kazuhiro Takahashi
    Pages 155-166
  10. Tatsuo Shimosawa, Katsuyuki Ando, Toshiro Fujita
    Pages 175-185
  11. Toshio Nishikimi, Noritoshi Nagaya, Kenji Kangawa, Hiroaki Matsuoka
    Pages 187-198
  12. Noritoshi Nagaya, Toshio Nishikimi, Kenji Kangawa
    Pages 199-214
  13. Back Matter
    Pages 215-219

About this book


Adrenomedullin was discovered in 1993 in an extract of human pheochromocytoma while monitoring cAMP levels in rat platelets. Adrenomedullin has attracted considerable interest among cardiologists due to its impact on the cardiovascular system which includes a decrease in blood pressure in vivo; an impact on vascular smooth muscle cells; increases cAMP levels; indirectly reduces blood pressure and has a role in the pathogenesis of arteriosclerosis.

Adrenomedullin in Cardiovascular Disease is an up-to-date review of the most relevant aspects of adrenomedullin. It encompasses a broad range of fields including biochemistry, molecular biology, physiology, pharmacology, pathophysiology of cardiovascular disease and clinical applications of adrenomedullin to cardiovascular disease.

Toshio Nishikimi, MD, PhD, is an Associate Professor in the Department of Hypertension and Cardiorenal Medicine, Dokkyo University School of Medicine, Tochigi, Japan.


arteriosclerosis biochemistry biology blood pressure cardiovascular cardiovascular system heart hypertension pathophysiology physiology smooth muscle vascular disease

Editors and affiliations

  • Toshio┬áNishikimi
    • 1
  1. 1.Department of Hypertension and Cardiorenal MedicineDokkyo University School of MedicineMibu, TochigiJapan

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media, Inc. 2005
  • Publisher Name Springer, Boston, MA
  • eBook Packages Medicine Medicine (R0)
  • Print ISBN 978-0-387-25404-3
  • Online ISBN 978-0-387-25405-0
  • Series Print ISSN 1566-0753
  • Buy this book on publisher's site