The Role of Nitric Oxide in Heart Failure

  • Bodh I. Jugdutt

Table of contents

  1. Front Matter
    Pages i-xiii
  2. NO and Pathophysiology of Heart Failure

    1. Front Matter
      Pages 1-1
    2. Karen L. Andrews, Chris R. Triggle, Anthie Ellis
      Pages 9-31
    3. Walter J. Paulus, Jean G. F. Bronzwaer
      Pages 33-45
    4. Hunter C. Champion, Michel W. Skaf, Joshua M. Hare
      Pages 81-92
    5. Jun-ichi Oyama, Stefan Frantz, Charles Blais Jr., Ralph A. Kelly, Todd Bourcier
      Pages 93-100
    6. Axel Linke, Fabio Recchia, Xiaoping Zhang, Thomas H. Hintze
      Pages 101-111
    7. Imran N. Mungrue, Mansoor Husain, Duncan J. Stewart
      Pages 113-128
  3. NO and Cardiovascular Therapeutics

    1. Front Matter
      Pages 129-129
    2. Bodh I. Jugdutt
      Pages 131-136
    3. Marc de Gasparo
      Pages 137-148
    4. David Alonso, Marek W. Radomski
      Pages 149-157
    5. Ascan Warnholtz, Nikolaus Tsilimingas, Maria Wendt, Thomas Münzel
      Pages 175-185
    6. Stephan von Haehling, Stefan D. Anker, Eberhard Bassenge
      Pages 187-194
    7. Suresh C. Tyagi, Melvin R. Hayden
      Pages 195-200
    8. Manoj M. Lalu, Wenjie Wang, Richard Schulz
      Pages 201-211
  4. Back Matter
    Pages 247-251

About this book


Nitric oxide (NO) is one of the most remarkable biological molecules characterized at the turn of XX century. Small in size, but ubiquitous and complex in its network of molecular, cellular and organ inter- tions, NO plays an important role in mammalian and non-mammalian biology. The scope and versatility of NO actions on the biological systems range from neuromodulation and regulation of cardiovascular homeostasis to cell signaling and immunity. An impressive array of physiologic and pathologic reactions are controlled by or associated with changes in the biological specter of NO. The “career” of NO in science started from a handful of publications written before 1986 to more than 52,000 contributions at the end of 2002 (Pubmed, National Library of Medicine). More than 15,000 publications deal with the effects of NO in the cardiovascular system. The NO field has been recently knighted with the 1998 Nobel Prize in Medicine awarded to R.F. Furchgott, F. Murad and L.J. Ignarro.


Angiotensin II atherosclerosis cardiovascular heart hypertension

Editors and affiliations

  • Bodh I. Jugdutt
    • 1
  1. 1.Cardiology Division Department of MedicineUniversity of AlbertaEdmontonCanada

Bibliographic information