Molecular Targeting and Signal Transduction

  • Rakesh Kumar

Part of the Cancer Treatment and Research book series (CTAR, volume 119)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Christopher J. Barnes, Rakesh Kumar
    Pages 1-13
  3. Hira Lal Goel, Lucia R. Languino
    Pages 15-31
  4. Oliver Stoeltzing, Lee M. Ellis
    Pages 33-58
  5. Lincoln A Edwards, Jennifer A Shabbits, Marcel Bally, Shoukat Dedhar
    Pages 59-75
  6. Ratna K. Vadlamudi, Rakesh Kumar
    Pages 77-88
  7. Martin Sattler, Patrick C. Ma, Ravi Salgia
    Pages 121-138
  8. Ian Anglin, Antonio Passaniti
    Pages 189-215
  9. Chenguan Wang, Zhiping Li, Maofu Fu, Toula Bouras, Richard G. Pestell
    Pages 217-237
  10. Ralph Arlinghaus, Tong Sun
    Pages 239-270
  11. Lakjaya Buluwela, Demetra Constantinidou, Joanna Pike, Simak Ali
    Pages 271-292
  12. Anna Bagnato, Pier Giorgio Natali
    Pages 293-314
  13. Wei Ding, Kathleen M. Mulder
    Pages 315-327
  14. Back Matter
    Pages 329-331

About this book


Our limited understanding of cellular regulatory signal-transduction-networks has been a barrier to progress in improving the overall cure-rate of human cancers. Delineation of the physiologic roles of the specific regulatory signaling components, with known association with metastatic phenotypes, is a highly promising area which will likely provide the next generation of targeted strategies in the future of molecular cancer medicine. These signaling components are likely to be used in diagnosis, prognosis, and as novel targets for therapeutic development.

This book brings together up-to-date summaries by leading cancer researchers on the major principles of cancer cell biology: survival, apoptosis, adhesion, and cell cycle deregulation. It is directed at clinicians and scientists working in the areas of experimental and molecular therapeutics, molecular medicine, translational cancer research, and bio-medical sciences in general.


Activation angiogenesis apoptosis biology cancer cancer research cell cell biology cell cycle metastasis molecular medicine ovarian cancer signal transduction

Editors and affiliations

  • Rakesh Kumar
    • 1
  1. 1.M. D. Anderson Cancer CenterThe University of TexasHoustonUSA

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 2004
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4020-7822-4
  • Online ISBN 978-1-4020-7847-7
  • Series Print ISSN 0927-3042
  • Buy this book on publisher's site