Neurodegeneration and Prion Disease

  • David R. Brown

Table of contents

  1. Front Matter
    Pages i-xv
  2. David R. Brown
    Pages 1-11
  3. Pawel P. Liberski, James W. Ironside
    Pages 13-48
  4. Ursula Unterberger, Till Voigtländer, Herbert Budka
    Pages 49-82
  5. Bernardino Ghetti, Pedro Piccardo, Orso Bugiani, Gianluigi Forloni, Michela Morbin, Mario Salmona et al.
    Pages 83-109
  6. Nikki K. MacLeod, Alex R. Johnston, John C. Curtis
    Pages 139-165
  7. Laura Vella, Andrew F. Hill, Roberto Cappai
    Pages 217-240
  8. David R. Brown
    Pages 241-271
  9. Neena Singh, Yaping Gu, Sharmila Bose, Subhabrata Basu, Xiu Luo, Richa Mishra et al.
    Pages 299-318
  10. Max Nunziante, Sabine Gilch, Hermann M. Schätzl
    Pages 379-405
  11. Ramanujan S. Hegde, Neena S. Rane
    Pages 407-450
  12. David R. Brown
    Pages 451-456
  13. Back Matter
    Pages 457-473

About this book


This volume provides an in-depth overview from world experts on prion disease. These fatal diseases include Creutzfeldt-Jakob disease, chronic wasting disease in deer, scrapie of sheep, bovine spongiform encephalopathy (mad cow’s disease) of cattle and related diseases. Understanding what causes neuronal death in these diseases is essential to both preventing and curing them. The most recent advances in understanding neuronal death in prion diseases are presented. Prion diseases serve as an experimental model for all neurodegenerative conditions. This book will provide understanding of neurodegeneration and provide an up-to-date record of the state of the art for other specialists and non-specialists in related fields.


cell culture cell death mitochondria mouse neuropathology oxidative stress pathology protein proteins

Editors and affiliations

  • David R. Brown
    • 1
  1. 1.University of BathUK

Bibliographic information