Cell Motility in Cancer Invasion and Metastasis

  • Alan Wells

Part of the Cancer Metastasis - Biology and Treatment book series (CMBT, volume 8)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Kun Yuan, Raj K. Singh, Gabriel Rezonzew, Gene P. Siegal
    Pages 25-54
  3. Wendy Ingman, Jeffrey Wyckoff, Chengsen Xue, Elaine Y. Lin, Weigang Wang, Sumanta Goswami et al.
    Pages 55-72
  4. Clayton Yates, Donna Beer Stolz, Linda Griffith
    Pages 73-88
  5. Elizabeth J. Joslin, Douglas A. Lauffenburger
    Pages 89-109
  6. Paolo M. Comoglio, Carla Boccaccio
    Pages 111-142
  7. William G. Stetler-Stevenson, Dong-Wan Seo
    Pages 143-158
  8. Isaac Rabinovitz, Arthur M. Mercurio
    Pages 159-187
  9. Amra Hajdo-Milašinović, Alexander E. Mertens, Irene H. L. Hamelers, John G. Collard
    Pages 189-220
  10. Michelle R. Stettner, Meera Natarajan, Candece L. Gladson
    Pages 221-243
  11. Sufi Mary Thomas, Jennifer Rubin Grandis
    Pages 245-264
  12. Anja Katrin Bosserhoff
    Pages 265-300
  13. Sourabh Kharait, Kien Tran, Clayton Yates, Alan Wells
    Pages 301-338
  14. Back Matter
    Pages 339-351

About this book


Cancer Morbidity and mortality result from invasive and metastatic spread. Currently, no therapies are aimed at the underlying mechanisms that enable this progression due to only nascent recognition of the distinct biology which occurs only during tumor dissemination. Recent advances have highlighted the central role of cell motility during the dynamic and transient process of tumor invasion and metastasis. This book includes state-of-the-art updates by international leaders in these studies. Chapters first present the novel model systems that enable new investigations and insights. Chapters then describe in depth the key processes and molecules that may be therapeutically targeted. Finally, the role of cell motility and its signals is explored in a number of key tumor types. This compilation should be useful to researchers in basic and translational oncology as well as those developing novel agents to prevent tumor invasion and metastasis.


biology carcinoma imaging morbidity tumorigenesis

Editors and affiliations

  • Alan Wells
    • 1
  1. 1.Department of Pathology, Pittsburgh VAMCUniversity of PittsburghUSA

Bibliographic information