Textbook of Coronary Thrombosis and Thrombolysis

  • Richard C. Becker

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 193)

Table of contents

  1. Front Matter
    Pages i-xxi
  2. Scientific Principles

    1. Front Matter
      Pages 1-1
    2. The Biochemistry of Thrombosis

      1. Frederick A. Spencer, Richard C. Becker
        Pages 5-13
      2. Pamela Sakkinen, Russell P. Tracy
        Pages 15-28
    3. Platelets

    4. Fibrinolysis

      1. H. Roger Lijnen
        Pages 53-64
      2. Daniel T. Eitzman, William P. Fay, David Ginsburg
        Pages 65-78
      3. Bruce A. Keyt, Ted W. Love
        Pages 101-120
    5. Vascular Biology

      1. Una S. Ryan
        Pages 123-138
      2. Harsch Sanchorawala, John F. Keaney Jr.
        Pages 139-153
      3. Marco N. Diaz, Richard A. Cohen
        Pages 155-168
    6. Experimental Models of Plaque Rupture, Thrombosis, and Thrombolysis

  3. Clinical Application of Scientific Principles

    1. Front Matter
      Pages 235-235
    2. Thrombolytic Agents

      1. H. Joost Kruik, Willemien J. Kollöffel, Freek W. A. Verheugt
        Pages 239-242
      2. Steven Vanderschueren, Désiré Collen
        Pages 257-262
      3. Christoph Bode, Thomas K. Nordt, Benedikt Kohler, W. Douglas Weaver, Richard W. Smalling
        Pages 263-268
      4. Steffen P. Christow, Dietrich C. Gulba
        Pages 269-282
    3. National Goals and Perspectives for Improving Patient Care: The National Heart Attack Alert Program

    4. Prehospital Strategies for the Treatement of Acute Myocardial Infarction

      1. Alfred E. R. Arnold, Eric Boersma, Maureen van der Vlugt, Maarten L. Simoons
        Pages 345-354
    5. Adjunctive Antithrombotic Strategies

    6. Plasma Markers of Infarction, Thrombosis, and Thrombolysis

      1. Sanjay Dixit, Allan S. Jaffe
        Pages 413-420
      2. L. Veronica Lee, Dana R. Abendschein, Paul R. Eisenberg
        Pages 421-447
      3. Dana R. Abendschein
        Pages 449-461
    7. Anticoagulation Monitoring

      1. James M. Wilson
        Pages 465-482
      2. Reza Khoshnevis, James J. Ferguson
        Pages 495-515
    8. Hemorrhagic Complications of Thrombolytic and Antithrombotic Therapy

      1. Cynthia M. Thaik, Patrick O’Gara
        Pages 519-544
    9. Gene Therapy in Vascular Disease

      1. Douglas W. Losordo, Jeffrey M. Isner
        Pages 547-560
      2. Elizabeth G. Nabel
        Pages 561-563
  4. New Dimensions

    1. Front Matter
      Pages 565-565
    2. Future Directions for Basic Investigational and Clinical Research

      1. Nikolaos G. Frangogiannis, Mark L. Entman
        Pages 569-584
      2. Linda R. Peterson
        Pages 585-610
  5. Evolution of Thrombocardiology

    1. Front Matter
      Pages 611-611
    2. Clinical Trial Design and Drug Development

      1. Mark C. Thel, Robert A. Harrington
        Pages 615-641

About this book


Teleologically, the hemostatic mechanism is among The of Coronary Thrombosis and the most fundamental yet complex physiologic pro- in essence, represents a heartfelt gift of cesses in humans. Early scientists and physicians were knowledge from a dedicated group of scientists and fascinated by the blood's ability to remain in a liquid clinicians, who collectively have set out on a mission state only to clot in response to vascular injury. The to minimize the societal impact of"hemostasis in the cellular and noncellular components of normal wrong place. " The book is divided into four distinct hemostasis took centuries to discover, and the intrica- sections: Part 1, Scientific Principles, lays down the cies of their delicate interactions are still being unrav- supporting foundation; Part 2, Clinical Application eled today. As is so often the case, an in-depth of Scientific Principles, places the knowledge base in appreciation of physiologic hemostasis, representing a a working perspective, directly applying science to basic life-sustaining sequence of events, paved the patient care; Part 3, New Dimensions, provides a way for understanding abnormal hemostasis or glimpse of tomorrow. Steering the field clear of se- pathologic thrombosis. Aristotle, Malpighi, and proclaimed victory and the dangers of complacency as Osier, representing but a few of the founding fathers we move into the 21st century, Part 4, Evolution of in the field, would undoubtedly be honored to see Thrombocardiology, focuses on laboratory standards, their observations form the template for lifesaving clinical trials, and drugs in development.


cardiology drugs gene therapy myocardial infarction plasma platelet thrombosis vascular disease

Editors and affiliations

  • Richard C. Becker
    • 1
    • 2
  1. 1.Cardiovascular Thrombosis Research CenterUSA
  2. 2.Coronary Care UnitUniversity of Massachusetts Medical SchoolWorcester

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 1997
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-0-7923-9923-0
  • Online ISBN 978-0-585-33754-8
  • Series Print ISSN 0166-9842
  • Buy this book on publisher's site