Signal Transduction in Cancer

  • David A. Frank

Part of the Cancer Treatment and Research book series (CTAR, volume 115)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Receptors

    1. Joshua B. Rubin, Rosalind A. Segal
      Pages 1-18
    2. Roy S. Herbst, Amir Onn, John Mendelsohn
      Pages 19-72
    3. Yansong Bian, Virginia Kaklamani, Jennifer Reich, Boris Pasche
      Pages 73-94
    4. Douglas W. Ball, Steven D. Leach
      Pages 95-121
  3. Intracellular Pathways

    1. Yoon S. Cho-Chung
      Pages 123-143
    2. Juan Paez, William R. Sellers
      Pages 145-167
    3. Patrice J. Morin, Ashani T. Weeraratna
      Pages 169-187
    4. Aylin S. Ülkü, Channing J. Der
      Pages 189-208
    5. Lili Yamasaki
      Pages 209-239
  4. Transcription Factors

  5. Cell Death Pathways

    1. Timothy F. Burns, Wafik S. El-Deiry
      Pages 319-343
    2. David K. Perry, Richard N. Kolesnick
      Pages 345-354
  6. Back Matter
    Pages 355-357

About this book


One of the most exciting areas of cancer research now is the development of agents which can target signal transduction pathways that are activated inappropriately in malignant cells. The understanding of the molecular abnormalities which distinguish malignant cells from their normal counterparts has grown tremendously.
This volume summarizes the current research on the role that signal transduction pathways play in the pathogenesis of cancer and how this knowledge may be used to develop the next generation of more effective and less toxic anticancer agents.
Series Editor comments:
"The biologic behavior of both normal and cancer cells is determined by critical signal transduction pathways. This text provides a comprehensive review of the field. Leading investigators discuss key molecules that may prove to be important diagnostic and/or therapeutic targets."


cell cell death hormones pathogenesis tumor

Editors and affiliations

  • David A. Frank
    • 1
  1. 1.Dana-Farber Cancer InstituteHarvard Medical SchoolBostonUSA

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 2003
  • Publisher Name Springer, Boston, MA
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-4020-7340-3
  • Online ISBN 978-0-306-48158-1
  • Series Print ISSN 0927-3042
  • Buy this book on publisher's site