© 2005

Infectious Diseases and Substance Abuse

  • Herman Friedman
  • Thomas W. Klein
  • Mauro Bendinelli

Part of the Infectious Agents and Pathogenesis book series (IAPA)

Table of contents

  1. Front Matter
    Pages i-xx
  2. Albert H. Avila, Norma C. Alonzo, Barbara M. Bayer
    Pages 1-11
  3. Gayle C. Baldwin, Michael D. Roth
    Pages 13-32
  4. Jerry L. Bulen, Peter G. Medveczky
    Pages 33-49
  5. Guy A. Cabral, Francine Marciano-Cabral
    Pages 51-65
  6. Herman Friedman, Catherine Newton, Thomas W. Klein
    Pages 67-75
  7. Susan Pross, Herman Friedman
    Pages 77-92
  8. Yoshimasa Yamamoto
    Pages 93-102
  9. Mohan L. Sopori, Seddigheh Razani-Boroujerdi, Shashi P. Singh
    Pages 103-109
  10. Filip Bednar, Amber D. Steele, David E. Kaminsky, Penelope C. Davey, Thomas J. Rogers
    Pages 111-123
  11. Sabita Roy, Jing-Hua Wang, Roderick A. Barke
    Pages 125-140
  12. Richard Weber, Ricardo Gomez
    Pages 149-158
  13. Yoshimasa Yamamoto, Herman Friedman
    Pages 159-169
  14. Zeki Yumuk
    Pages 171-177
  15. Ping Zhang, Gregory J. Bagby, Jay K. Kolls, Lee J. Quinton, Steve Nelson
    Pages 179-195
  16. Back Matter
    Pages 197-211

About this book


The use of recreational drugs of abuse by large numbers of individuals in this country and abroad has aroused serious concerns about the consequences of this activity. For example, it is recognized that marijuana is currently widely used as a recreational drug in the United States as well as other countries. Similarly, abuse of cocaine, especially crack cocaine, is considered to be an epidemic. “The war on drugs” by the US Government was directly aimed at the illicit use of cocaine, marijuana, and opiates as well as other drugs of abuse. Furthermore, alcohol is also considered a major problem of abuse in this country as well as in many other countries. It is estimated there are at least 10 million alcoholics in the United States alone. A signi?cant portion of those hospitalized with infectious diseases are alcoholics. Similarly, there have been many reports of association between marijuana use and increased susceptibility to infection as well as a re- tion between use of opiates and infections. The relationship between drug abuse and increased incidence of various infections has stimulated increased investi- tion of whether and how such drugs affect immune function, especially imp- tant for resistance against infectious agents. During the last decades, a wide variety of studies have shown that drugs of abuse, including marijuana, cocaine, or opiates, as well as alcohol, alter both neurophysiological as well as pathological responses of individuals.


Chemokine HIV HIV infection bacteria infection infections infectious infectious disease infectious diseases interferon virus

Editors and affiliations

  • Herman Friedman
    • 1
  • Thomas W. Klein
    • 1
  • Mauro Bendinelli
    • 2
  1. 1.Department of Medical Microbiology and ImmunologyUniversity of South Florida College of MedicineTampa
  2. 2.Department of Experimental PathologyUniversity of PisaPisaItaly

Bibliographic information