SIRT6 Activities in DNA Damage Repair and Premature Aging

Functions of SIRT6

  • Shrestha¬†Ghosh

Part of the Springer Theses book series (Springer Theses)

Table of contents

About this book


This book illustrates the activities of mammalian sirtuin SIRT6 in connection with DNA damage repair and premature aging. It mainly presents research on the nuclear lamin A, notably the upregulation of p53 and acetylation etc. Taken together, these studies reveal the various regulatory roles of SIRT6, which are of substantial biological relevance in DNA damage repair, aging and longevity, and can have significant implications in devising therapeutic strategies to combat age-associated pathologies. Given its scope, the book offers a valuable resource for students and researchers in the fields of genetics, cell biology, molecular biology etc.


SIRT6 Activities DNA Damage Repair Premature Aging Mammalian sirtuin ageassociated pathologies

Authors and affiliations

  • Shrestha¬†Ghosh
    • 1
  1. 1.Dana-Farber Cancer InstituteBostonUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-981-32-9266-6
  • Online ISBN 978-981-32-9267-3
  • Series Print ISSN 2190-5053
  • Series Online ISSN 2190-5061
  • Buy this book on publisher's site