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Cancer Cell Metabolism: A Potential Target for Cancer Therapy

  • Dhruv Kumar
Book

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Sibi Raj, Vaishali Chandel, Dhruv Kumar
    Pages 1-13
  3. Samyukta Narayanan, Anirudh Santhoshkumar, Srijit Ray, Sitaram Harihar
    Pages 15-26
  4. Sandesh Kumar Patel, Deepanshu Verma, Neha Garg
    Pages 27-37
  5. Anthony Michael Alvarado, Levi Kent Arnold, Sufi Mary Thomas
    Pages 39-53
  6. Satish S. Poojary, Maryam Ghufran, Ananya Choudhary, Mehreen Aftab
    Pages 55-63
  7. Diego A. Pedroza, Vaishali Chandel, Dhruv Kumar, Prakash Doddapattar, M. S. Biradar, Rajkumar Lakshmanaswamy et al.
    Pages 65-87
  8. Vaishali Chandel, Sibi Raj, Ramesh Choudhary, Dhruv Kumar
    Pages 89-102
  9. Narayan Sugandha, Lovika Mittal, Amit Awasthi, Shailendra Asthana
    Pages 103-126
  10. Niraj Kumar Jha, Saurabh Kumar Jha, Ankur Sharma, Rahul Yadav, Pratibha Pandey, Kavindra Kumar Kesari et al.
    Pages 127-146
  11. Saurabh Kumar Jha, Rahul Yadav, Kumari Swati, Niraj Kumar Jha, Ankur Sharma, Fahad Khan et al.
    Pages 147-165
  12. Abhijeet Kumar, Anil Kumar Singh, Mukul Kumar Gautam, Garima Tripathi
    Pages 167-184

About this book

Introduction

This book illustrates various aspects of cancer cell metabolism, including metabolic regulation in solid tumours vs. non-solid tumours, the molecular pathways involved in its metabolism, and the role of the tumour microenvironment in the regulation of cancer cell metabolism. It summarizes the complexity of cancer cell metabolism in terms of the switch from anaerobic to aerobic glycolysis and how mitochondrial damage promotes aerobic glycolysis in cancer cells. The respective chapters provide the latest information on the metabolic remodelling of cancer cells and elucidate the important role of the signalling pathways in reprogramming of cancer cell metabolism. In addition, the book highlights the role of autophagy in cancer cell metabolism, and how metabolic crosstalk between cancer cells and cancer-associated fibroblasts promotes cancer cell progression. In closing, it summarizes recent advancements in drug development through targeting cancer metabolism.

Keywords

Cancer cell metabolism Metabolic alteration Targeting metabolic alteration anti-cancer drug therapy Diagnostic markers

Editors and affiliations

  • Dhruv Kumar
    • 1
  1. 1.Amity Institute of Molecular Medicine & Stem Cell Research (AIMMSCR)Amity University Uttar Pradesh (AUUP)NoidaIndia

Bibliographic information