© 2019

Zinc Signaling

  • Toshiyuki Fukada
  • Taiho Kambe

Table of contents

  1. Front Matter
    Pages i-viii
  2. Taiho Kambe, Eisuke Suzuki, Taiki Komori
    Pages 23-56
  3. Debabrata Chowdhury, George S. Deepe Jr, Kavitha Subramanian Vignesh
    Pages 57-77
  4. Keigo Nishida, Michiko Kato, Ryota Uchida
    Pages 79-97
  5. Atsuko Kageyama, Takafumi Namiki, Junya Ito, Naomi Kashiwazaki
    Pages 99-121
  6. Kristyn Gumpper, Jianjie Ma
    Pages 123-137
  7. Belma Turan, Deniz Billur, Yusuf Olgar
    Pages 139-164
  8. Stuart D. Portbury, Ashley I. Bush, Paul A. Adlard
    Pages 201-228
  9. Ayako Fukunaka, Yoshio Fujitani
    Pages 229-242
  10. Martina Maywald, Lothar Rink
    Pages 243-277
  11. Sannette C. Hall, Daren L. Knoell
    Pages 279-304
  12. Bum-Ho Bin, Mi-Gi Lee, Takafumi Hara, Teruhisa Takagishi, Toshiyuki Fukada
    Pages 305-317
  13. Thirayost Nimmanon, Kathryn M. Taylor
    Pages 319-345
  14. Michal Hershfinkel, Johnny Iv, Shannon L. Kelleher
    Pages 347-363
  15. Jiyao Yu, Christoph J. Fahrni
    Pages 365-388
  16. Hak Chung, Amanda J. Bird
    Pages 389-410

About this book


This book, now in an extensively revised second edition, describes the crucial role of zinc signaling in biological processes on a molecular and physiological basis. Global leaders in the field review the latest knowledge, including the very significant advances in understanding that have been achieved since publication of the first edition. Detailed information is provided on all the essentials of zinc signaling, covering molecular aspects and the roles of zinc transporters, the zinc sensing receptor, and metallothioneins. Detection techniques for zinc signals, involving genetically encoded and chemical probes, are also described. The critical contributions of the zinc signal in maintaining health and the adverse consequences of any imbalance in the signal are then thoroughly addressed. Here, readers will find up-to-date information on the significance of the zinc signal in a wide range of conditions, including cardiovascular disorders, neurodegenerative diseases, diabetes, autoimmune diseases, inflammatory conditions, skin disease, osteoarthritis, and cancer. The book will be of value for researchers, clinicians, and advanced students.


Zinc biology Zinc signals Zinc transporters Metallothionein Neuron Diabetes Cancer Skin Bone Immunology

Editors and affiliations

  • Toshiyuki Fukada
    • 1
  • Taiho Kambe
    • 2
  1. 1.Molecular and Cellular Physiology Faculty of Pharmaceutical SciencesTokushima Bunri UniversityTokushimaJapan
  2. 2.Division of Integrated Life Science Graduate School of BiostudiesKyoto UniversityKyotoJapan

About the editors

Professor. Toshiyuki Fukada, Ph.D., Faculty of Pharmaceutical Sciences, Molecular and Cellular Physiology, Tokushima Bunri University, Japan.

Associate professor. Taiho Kambe, Ph.D., Department of Applied Molecular Biology, Division of Integrated Life Science, Graduate School of Biostudies, Kyoto University, Japan. 


Bibliographic information