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Aldehyde Dehydrogenases

From Alcohol Metabolism to Human Health and Precision Medicine

  • Jun Ren
  • Yingmei Zhang
  • Junbo Ge
Book

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1193)

Table of contents

  1. Front Matter
    Pages i-xx
  2. Mahmoud M. El-Mas, Abdel A. Abdel-Rahman
    Pages 1-33
  3. Pritam Sinharoy, Stacy L. McAllister, Megana Vasu, Eric R. Gross
    Pages 35-52
  4. Che-Hong Chen, Julio C. B. Ferreira, Daria Mochly-Rosen
    Pages 53-67
  5. Wenjia Li, Cheng Shen, Lei Yin, Junbo Ge, Aijun Sun
    Pages 89-106
  6. Srikar Munukutla, Guodong Pan, Suresh S. Palaniyandi
    Pages 155-174
  7. Jiaojiao Pang, Yue Zheng, Qi Han, Ying Zhang, Ruru Sun, Jiali Wang et al.
    Pages 175-194
  8. Haixia Xu, Yingmei Zhang, Jun Ren
    Pages 195-210
  9. Li-Shun Wang, Zhao-Xia Wu
    Pages 221-228

About this book

Introduction

This volume covers the science of ALDH enzymes in relation to chronic disease processes and the future therapeutic potentials of targeting ALDH in these processes. It thoroughly reviews the roles of ALDH family in alcohol metabolism, as well as recent findings of their emerging roles in a variety of human pathologies such as cardiovascular diseases, diabetes, obesity, stroke, cancer, liver diseases and kidney diseases. Delicate contribution of ALDH enzymes in the therapeutics against chronic diseases is also discussed. It demonstrates the unique value of targeting genetic polymorphism in ALDH enzymes in personalized medicine. The book will appeal to scientists, physicians, graduate and professional students in the fields of ALDH enzymes, alcohol metabolism, cardiometabolic and other chronic diseases. Pharmaceutical and other companies developing new tools for cardiometabolic and chronic diseases treatment will also find this a valuable resource.

Keywords

Aldehyde dehydrogenases ALDH enzymes ALDH2 Alcohol metabolism Cardiometabolic and chronic diseases Genetic polymorphism

Editors and affiliations

  • Jun Ren
    • 1
  • Yingmei Zhang
    • 2
  • Junbo Ge
    • 3
  1. 1.Department of Cardiology, Shanghai Institute of Cardiovascular DiseasesZhongshan Hospital, Fudan UniversityShanghaiChina
  2. 2.Department of Cardiology, Shanghai Institute of Cardiovascular DiseasesZhongshan Hospital, Fudan UniversityShanghaiChina
  3. 3.Department of Cardiology, Shanghai Institute of Cardiovascular DiseasesZhongshan Hospital, Fudan UniversityShanghaiChina

Bibliographic information

  • DOI https://doi.org/10.1007/978-981-13-6260-6
  • Copyright Information Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-981-13-6259-0
  • Online ISBN 978-981-13-6260-6
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • Buy this book on publisher's site