Smooth Muscle Spontaneous Activity

Physiological and Pathological Modulation

  • Hikaru Hashitani
  • Richard J. Lang

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1124)

Table of contents

  1. Front Matter
    Pages i-xix
  2. Gastrointestinal Tract

  3. Urinary Tract

    1. Front Matter
      Pages 75-75
    2. Christopher H. Fry, Karen D. McCloskey
      Pages 121-147
    3. Gerard P. Sergeant, Mark A. Hollywood, Keith D. Thornbury
      Pages 149-167
  4. Reproductive Organs

    1. Front Matter
      Pages 169-169
    2. Keith D. Thornbury, Mark A. Hollywood, Gerard P. Sergeant
      Pages 171-194
    3. Basu Chakrabarty, Sophie Lee, Betty Exintaris
      Pages 195-215
    4. Mitsue Takeya, Tokumasa Hayashi, Hikaru Hashitani, Makoto Takano
      Pages 217-231
    5. Susan Wray, Clodagh Prendergast
      Pages 233-263
    6. Rose E. Dixon, Sung Jin Hwang, Bo Hyun Kim, Kenton M. Sanders, Sean M. Ward
      Pages 265-294
  5. Blood Vessels

    1. Front Matter
      Pages 295-295
    2. William C. Cole, Grant R. Gordon, Andrew P. Braun
      Pages 297-312
    3. Dirk F. van Helden, Mohammad S. Imtiaz
      Pages 313-328
    4. Pierre-Yves von der Weid
      Pages 357-377
  6. Airways

    1. Front Matter
      Pages 379-379
    2. Maggie Lam, Emma Lamanna, Jane E. Bourke
      Pages 381-422
  7. Back Matter
    Pages 423-427

About this book


This book presents the commonality and heterogeneity of the mechanisms underlying smooth muscle spontaneous activity in various smooth muscle organs and in addition discusses their malfunctions in disease and their potential as novel therapeutic targets. To facilitate understanding, the volume is divided into five parts and covers 16 organs: airways, phasic muscle, tonic muscle, renal pelvis, ureter, urinary bladder, urethra, corporal tissue, prostate, uterus, oviducts, seminal vesicle, artery, vein, microvasculature, and lymphatic vessels. This structure will help readers to comprehend the most up-to-date information on the similarities and differences in the contractile mechanisms driving various smooth muscles as well as their potential manipulations in particular visceral organ pathologies. The vast advancements in gene, electrical recording, and imaging technologies in this field are also discussed, with review of past achievements and consideration of likely future developments. This book will be of worldwide interest to clinicians, students, and researchers alike. 


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Editors and affiliations

  • Hikaru Hashitani
    • 1
  • Richard J. Lang
    • 2
  1. 1.Nagoya City UniversityNagoyaJapan
  2. 2.Monash UniversityMelbourneAustralia

Bibliographic information