© 2018

Molecular Basis and Emerging Strategies for Anti-aging Interventions

  • Syed Ibrahim Rizvi
  • Ufuk Çakatay


  • The book provides a compilation of major approaches on current anti-aging interventions

  • It provides the current understanding of the underlying principle, possible target, implementation approach and efficacy of the various anti-aging strategies

  • It highlights the use of various geroprotectives and senolytics as an anti-aging drugs


Table of contents

  1. Front Matter
    Pages i-xiv
  2. Banu Orta Yilmaz, Melike Erkan
    Pages 35-45
  3. Bhisham Narayan Singh, Anubha Joshi, Sarada Prasanna Mallick, Pradeep Srivastava
    Pages 47-66
  4. Janice Wong, Anam Qudrat, Abdullah Al Mosabbir, Kevin Truong
    Pages 67-82
  5. Mustafa Erinc Sitar, Elcin Akduman Alasehir, Belkiz Ongen Ipek
    Pages 111-132
  6. Hale Z. Toklu, Almari Ginory
    Pages 133-149
  7. Komal Saraswat, Raushan Kumar, Syed Ibrahim Rizvi
    Pages 151-160
  8. Abhishek Kumar Singh, Sandeep Singh, Syed Ibrahim Rizvi
    Pages 161-174
  9. Apramita Chand, Pragin Chettiyankandy, Maheswata Moharana, Satya Narayan Sahu, Sukanta Kumar Pradhan, Subrat Kumar Pattanayak et al.
    Pages 175-193
  10. Gurcharan Kaur, Taranjeet Kaur, Anuradha Sharma, Shaffi Manchanda, Harpal Singh, Shikha Kalotra et al.
    Pages 195-215
  11. Kalaiselvi Periandavan, Prema Velusamy
    Pages 267-279
  12. Kanti Bhooshan Pandey, Syed Ibrahim Rizvi
    Pages 297-304

About this book


This book describes the nature of aging, age-related disorders, and the molecular principles of emerging strategies for anti-aging interventions, while also discussing the discovery of targets for geroprotective drugs. Although significant medical advances in the treatment and eradication of life-threatening conditions such as cardiovascular and infectious disease have been made over the past five decades, the prevalence of age-related disorders still remains high in older populations. Intervening into aging is the next frontier in contemporary medicine, and will be of increasing importance over time, as other sources of poor health are combated more and more successfully. Given the universal interest in anti-aging strategies, the book will appeal to a very broad audience. It addresses a diverse range of anti-aging interventions – including stem cells, autophagy, senolytics, anti-inflammatory methods, and telomerase induction – that will be of interest to scientists and researchers from various disciplines in the life sciences. 


Anti-aging caloric restriction polyphenols lifespan geroprotection

Editors and affiliations

  • Syed Ibrahim Rizvi
    • 1
  • Ufuk Çakatay
    • 2
  1. 1.Department of BiochemistryUniversity of AllahabadAllahabadIndia
  2. 2.Medical BiochemistryIstanbul University, CerrahpasaIstanbulTurkey

About the editors

Dr. Syed Ibrahim Rizvi is a Professor of Biochemistry at the University of Allahabad, India. He has been a visiting Professor at several universities including the University of Athens (Greece), University of Nice (France), University of Pisa, University of Milan, University of Rome (Italy), Istanbul University (Turkey), Research Centre for Natural Sciences, Budapest (Hungary) and Bangladesh University of Health Sciences, Dhaka. Prof. Rizvi is a grantee of the International Foundation for Science, Sweden. His research interests include aging mechanisms, anti-aging interventions, metabolic diseases, and natural products. To date, he has published 145 research papers, 10 book chapters and a large number of popular science articles. He has been awarded fellowships/grants by the European Molecular Biology Organisation (EMBO), Federation of European Biochemical Societies (FEBS), International Cell Research Organisation, Organization for the Prevention of Chemical Weapons (OPCW), the Hague (Netherlands), Department of Science and Technology, Govt. of India, and University Grants Commission, India. He has received the Young Scientist Project Award from the Department of Science and Technology, Govt. of India and was conferred the Academic Excellence Award by the University of Allahabad in 2016. Prof. Rizvi serves on the editorial/review boards of several leading research journals, and his work has been highlighted in the BBC (London) and other print and TV media. Prof Rizvi has 30 years of teaching/research experience. 

Dr. Ufuk Çakatay is a senior scientist at the Department of Medical Biochemistry, Cerrahpaşa Faculty of Medicine, Istanbul University. Previously, he worked as an Associate Professor at the Central Laboratory of Clinical Biochemistry, Istanbul Faculty of Medicine. He graduated from the Department of Biology, Faculty of Science and received his Ph.D. degree from the Department of Medical Biochemistry, Cerrahpaşa Faculty of Medicine. His research interests include the optimization of bioanalytic methods for measuring oxidative stress, experimental animal models of aging, and age-related disorders. He has a long-standing interest in various protein oxidation biomarkers such as protein carbonyl groups, protein hydroperoxides, advanced oxidation protein products, dityrosine, and nitrotyrosine. Professor Çakatay has authored more than 80 publications, which include research papers, book chapters, editorials and invited reviews on free radical biology, aging, diabetes, and biological activity of alpha-lipoic acid. He has served as a guest editor, referee or member of the editorial board for more than 50 journals. He has received various prestigious awards such as the top reviewer award from Elsevier Science Publishing (2008) and serves on Istanbul University’s Committee on Animal Research and Ethics. 

Bibliographic information