Role of Tyrosine Kinases in Gastrointestinal Malignancies

  • Ganji Purnachandra┬áNagaraju

Table of contents

  1. Front Matter
    Pages i-xv
  2. Ranjeet Kumar, Akriti Gupta Jain, Mamoon Ur Rashid, Saeed Ali, Neelam Khetpal, Ishtiaq Hussain et al.
    Pages 1-14
  3. Neelam Khetpal, Saeed Ali, Ranjeet Kumar, Mamoon Ur Rashid, Sarfraz Ahmad
    Pages 29-56
  4. Saimila Momin, Ganji Purnachandra Nagaraju
    Pages 57-61
  5. Tapan K. Barik, Surya N. Swain
    Pages 71-81
  6. Gowru Srivani, Shipra Reddy Bethi, Sheik Aliya, Afroz Alam, Ganji Purnachandra Nagaraju
    Pages 83-96
  7. Vidya Mukhund, Afroz Alam, Ganji Purnachandra Nagaraju
    Pages 97-105
  8. Mamoon Ur Rashid, Ishtiaq Hussain, Sundas Jehanzeb, Saeed Ali, Akriti Gupta Jain, Ranjeet Kumar et al.
    Pages 115-140
  9. Begum Dariya, Neha Merchant, Sheik Aliya, Afroz Alam, Ganji Purnachandra Nagaraju
    Pages 141-170
  10. Saimila Momin, Ganji Purnachandra Nagaraju
    Pages 171-178
  11. Siva K. P. Konduru, Santoshi Muppala
    Pages 179-190
  12. Allyson E. Koyen, Geraldine Nabeta, Stevin Bienfait, Ashley J. Schlafstein, David S. Yu, Waaqo Daddacha
    Pages 225-234
  13. Suvani Subhadarshini, Neha Merchant, Ganji Seeta Rama Raju
    Pages 235-241

About this book


The aim of this book is to provide comprehensive overview of the role of different tyrosine kinases in the progression and metastasis of various cancers of the gastrointestinal tract such as esophagus, liver, pancreas, stomach, and colorectal. Activation of various signaling pathways and tyrosine kinases are responsible for resistance to chemo and radiotherapy in these gastrointestinal malignancies. Targeting these tyrosine kinases, which regulate the activities of survival pathways in growth, and metastasis is a rational strategy in gastrointestinal cancer therapy.

Each chapter embedded in this book covers information pertaining to a specific tyrosine kinase and its impact on various malignancies, which is not only significant for basic and clinical research investigations but will also be valued by students at advanced undergraduate to postgraduate levels.


Tyrosine kinases Gastrointestinal malignancies Tyrosine kinase receptors Tyrosine Kinase inhibitors Drug resistance

Editors and affiliations

  • Ganji Purnachandra┬áNagaraju
    • 1
  1. 1.Department of Hematology and Medical Oncology, School of Medicine, Winship Cancer InstituteEmory UniversityAtlantaUSA

Bibliographic information