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HIV Vaccines and Cure

The Path Towards Finding an Effective Cure and Vaccine

  • Linqi Zhang
  • Sharon R. Lewin

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 1075)

Table of contents

  1. Front Matter
    Pages i-xv
  2. HIV Vaccines

    1. Front Matter
      Pages 1-1
    2. Elizabeth Heger, Alexandra Schuetz, Sandhya Vasan
      Pages 3-30
    3. Beatriz Mothe, Christian Brander
      Pages 31-51
    4. Zhiwei Chen
      Pages 97-124
    5. M. Kumi Smith, Britta L. Jewell, Timothy B. Hallett, Myron S. Cohen
      Pages 125-162
  3. HIV Cure

    1. Front Matter
      Pages 163-163
    2. Julia Marsh Sung, David M. Margolis
      Pages 165-185
    3. Georges Khoury, Gilles Darcis, Michelle Y. Lee, Sophie Bouchat, Benoit Van Driessche, Damian F. J. Purcell et al.
      Pages 187-212
    4. Anastassia Mikhailova, Jose Carlos Valle-Casuso, Asier Sáez-Cirión
      Pages 213-239
    5. James B. Whitney, R. Brad Jones
      Pages 241-263
    6. Bethany A. Horsburgh, Sarah Palmer
      Pages 265-284
    7. Thomas Aagaard Rasmussen, Ole S. Søgaard
      Pages 285-318

About this book

Introduction

This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.

Keywords

HIV Cure Latency Vaccine Antibody

Editors and affiliations

  • Linqi Zhang
    • 1
  • Sharon R. Lewin
    • 2
  1. 1.Comprehensive AIDS Research Center, School of MedicineTsinghua UniversityBeijingChina
  2. 2.The Peter Doherty Institute for Infection and ImmunityUniversity of Melbourne and Royal Melbourne HospitalMelbourneAustralia

Bibliographic information

  • DOI https://doi.org/10.1007/978-981-13-0484-2
  • Copyright Information Springer Nature Singapore Pte Ltd. 2018
  • Publisher Name Springer, Singapore
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-981-13-0483-5
  • Online ISBN 978-981-13-0484-2
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • Buy this book on publisher's site