Advanced Optical Methods for Brain Imaging

  • Fu-Jen Kao
  • Gerd Keiser
  • Ankur Gogoi

Part of the Progress in Optical Science and Photonics book series (POSP, volume 5)

Table of contents

  1. Front Matter
    Pages i-xx
  2. Overview

    1. Front Matter
      Pages 1-1
    2. Ankur Gogoi, Gerd Keiser, Fu-Jen Kao, Ann-Shyn Chiang
      Pages 3-45
  3. Advanced Optical Microscopy Methods

    1. Front Matter
      Pages 47-47
    2. Bernhard Baumann
      Pages 49-68
    3. Monika Pawłowska, Marzena Stefaniuk, Diana Legutko, Leszek Kaczmarek
      Pages 69-81
    4. Wolfgang Becker, Samuel Frere, Inna Slutsky
      Pages 103-110
  4. Multiphoton Microscopy

    1. Front Matter
      Pages 111-111
    2. Serena Bovetti, Claudio Moretti, Tommaso Fellin
      Pages 123-141
    3. Michael Castanares, Greg J. Stuart, Vincent Daria
      Pages 143-165
    4. Weijian Zong, Liangyi Chen
      Pages 167-187
  5. Super-Resolution Microscopy

    1. Front Matter
      Pages 219-219
    2. Boris Egger, Simon G. Sprecher
      Pages 245-258
    3. Jae-Byum Chang
      Pages 259-273
  6. Supporting Technologies in Brain Imaging

    1. Front Matter
      Pages 275-275
    2. Juan M. Bueno
      Pages 277-294

About this book


This book highlights the rapidly developing field of advanced optical methods for structural and functional brain imaging. As is known, the brain is the most poorly understood organ of a living body. It is indeed the most complex structure in the known universe and, thus, mapping of the brain has become one of the most exciting frontlines of contemporary research. Starting from the fundamentals of the brain, neurons and synapses, this book presents a streamlined and focused coverage of the core principles, theoretical and experimental approaches, and state-of-the-art applications of most of the currently used imaging methods in brain research. It presents contributions from international leaders on different photonics-based brain imaging modalities and techniques. Included are comprehensive descriptions of many of the technology driven spectacular advances made over the past few years that have allowed novel insights of the structural and functional details of neurons.

The book is targeted at researchers, engineers and scientists who are working in the field of brain imaging, neuroscience and connectomics. Although this book is not intended to serve as a textbook, it will appeal to undergraduate students engaged in the specialization of brain imaging.


Superresolution microscopy STED microscopy STORM microscopy Light Sheet microscopy FLIM/FRET microscopy Multiphoton microscopy SRS microscopy Adaptive Optics Artificial Neural Network Ultrasensitive fluorescent proteins Optically Controllable Proteins Whole-brain functional imaging

Editors and affiliations

  • Fu-Jen Kao
    • 1
  • Gerd Keiser
    • 2
  • Ankur Gogoi
    • 3
  1. 1.Institute of BiophotonicsNational Yang-Ming UniversityTaipeiTaiwan
  2. 2.Department of Electrical and Computer EngineeringBoston UniversityBostonUSA
  3. 3.Institute of BiophotonicsNational Yang-Ming UniversityTaipeiTaiwan

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Engineering Engineering (R0)
  • Print ISBN 978-981-10-9019-6
  • Online ISBN 978-981-10-9020-2
  • Series Print ISSN 2363-5096
  • Series Online ISSN 2363-510X
  • Buy this book on publisher's site