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Multiscale Mechanobiology in Tissue Engineering

  • Damien Lacroix
  • Marzia Brunelli
  • Cécile Perrault
  • Adrien Baldit
  • Maryam Shariatzadeh
  • Ana Campos Marin
  • Andre Castro
  • Sara Barreto

Part of the Frontiers of Biomechanics book series (FB, volume 3)

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Marzia Brunelli, Cécile Perrault, Damien Lacroix
    Pages 1-22
  3. Adrien Baldit, Marzia Brunelli, Ana Campos Marin, Damien Lacroix
    Pages 23-36
  4. Marzia Brunelli, Cécile Perrault, Damien Lacroix
    Pages 37-57
  5. Maryam Shariatzadeh, Adrien Baldit, Cécile Perrault, Damien Lacroix
    Pages 105-125
  6. Maryam Shariatzadeh, Cécile Perrault, Damien Lacroix
    Pages 127-142
  7. Andre Castro, Maryam Shariatzadeh, Damien Lacroix
    Pages 143-158
  8. Sara Barreto, Damien Lacroix
    Pages 159-179
  9. Back Matter
    Pages 201-203

About this book

Introduction

This book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level. The book contributes to a better understanding of the design and use of bioreactors for tissue engineering and the use of mechanical loading to optimize in vitro cell culture conditions. It covers experimental and computational approaches and the combination of both to show the benefits that computational modelling can bring to experimentalists when studying in vitro cell culture within a scaffold. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, this work provides a novel approach to the use of engineering tools for the optimization of biological processes and its application to regenerative medicine. The volume is a valuable resource for researchers and graduate students studying mechanobiology and tissue engineering. For undergraduate students it also provides deep insight into tissue engineering and its use in the design of bioreactors. The book is supplemented with extensive references for all chapters to help the reader to progress through the study of each topic.

Keywords

Tissue engineering Computational simulations Multiscale approach Bioreactor design Cell mechanics

Authors and affiliations

  • Damien Lacroix
    • 1
  • Marzia Brunelli
    • 2
  • Cécile Perrault
    • 3
  • Adrien Baldit
    • 4
  • Maryam Shariatzadeh
    • 5
  • Ana Campos Marin
    • 6
  • Andre Castro
    • 7
  • Sara Barreto
    • 8
  1. 1.INSIGNEO Institute for in silico MedicineThe University of SheffieldSheffieldUnited Kingdom
  2. 2.INSIGNEO Institute for in silico MedicineThe University of SheffieldSheffieldUnited Kingdom
  3. 3.INSIGNEO Institute for in silico MedicineThe University of SheffieldSheffieldUnited Kingdom
  4. 4.INSIGNEO Institute for in silico MedicineThe University of SheffieldSheffieldUnited Kingdom
  5. 5.INSIGNEO Institute for in silico MedicineThe University of SheffieldSheffieldUnited Kingdom
  6. 6.INSIGNEO Institute for in silico MedicineThe University of SheffieldSheffieldUnited Kingdom
  7. 7.INSIGNEO Institute for in silico MedicineThe University of SheffieldSheffieldUnited Kingdom
  8. 8.INSIGNEO Institute for in silico MedicineThe University of SheffieldSheffieldUnited Kingdom

Bibliographic information

  • DOI https://doi.org/10.1007/978-981-10-8075-3
  • Copyright Information Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Engineering
  • Print ISBN 978-981-10-8074-6
  • Online ISBN 978-981-10-8075-3
  • Series Print ISSN 2199-8515
  • Series Online ISSN 2199-8523
  • Buy this book on publisher's site