Understanding Depression

Volume 2. Clinical Manifestations, Diagnosis and Treatment

  • Yong-Ku Kim

Table of contents

  1. Front Matter
    Pages i-xiii
  2. Diagnostic Issues of Depression

  3. Clinical Manifestations of Depression

    1. Front Matter
      Pages 97-97
    2. Seung-Gul Kang, Heon-Jeong Lee, Leen Kim, John Weyl Winkelman
      Pages 113-121
    3. Pierre A. Geoffroy, Sunthavy Yeim
      Pages 123-141
  4. Complicated Clinical Manifestations of Depression

    1. Front Matter
      Pages 161-161
    2. Renzo Bianchi, Irvin Sam Schonfeld, Eric Laurent
      Pages 187-202
    3. Young Sup Woo, Won-Myong Bahk
      Pages 203-220
  5. Therapeutic Issues of Depression

    1. Front Matter
      Pages 221-221
    2. Samuel T. Wilkinson, Robert B. Ostroff, Rachel B. Katz, John H. Krystal
      Pages 223-239
    3. Deepali Gupta, Radhakrishnan Mahesh
      Pages 241-255
    4. Laura Orsolini, Federica Vellante, Alessandro Valchera, Michele Fornaro, Alessandro Carano, Maurizio Pompili et al.
      Pages 257-268
    5. Rafael C. R. Freire, Patricia C. Cirillo, Antonio E. Nardi
      Pages 277-288
  6. Samuel T. Wilkinson, Robert B. Ostroff, Rachel B. Katz, John H. Krystal
    Pages E1-E1
  7. Back Matter
    Pages 329-333

About this book


This book, in two volumes, focuses on contemporary issues and dilemmas in relation to depression. The aim is to equip readers with an up-to-date understanding of the clinical and neurobiological underpinnings of depression, the clinical manifestations, and the development of more effective treatments. This second volume is devoted specifically to clinical and management issues. Readers will find detailed information on a wide range of frequently encountered and more complicated clinical presentations, with examination of risk factors and links to other conditions. Diagnostic aspects, including progress toward biological classification and the role of neuroimaging, are explored. Current trends in therapy are examined at length, drawing on the latest evidence and covering not only antidepressant medications but also the roles of neurostimulation, combined pharmacotherapy and psychotherapy, mindfulness-based cognitive therapy, and complementary and alternative medicine. The companion volume is dedicated to the underlying biomedical and neurobiological basis of depression. Understanding Depression will be an excellent source of information for both researchers and practitioners in the field.


Major depression and bipolar depression Biomarkers Diagnosis of depression Application of neuroimaging Anhedonia Sleep disorders Chonobiology Suicide Cognitive dimension Link with cardiovascular disease Bunout syndrome Link with obesity Ketamine Antidepressant therapy Treatment-resistant depression (TRD) Combination therapy Complementary and alternative medicine (CAM)

Editors and affiliations

  • Yong-Ku Kim
    • 1
  1. 1.College of MedicineKorea UniversityKyonggi-doKorea (Republic of)

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2018
  • Publisher Name Springer, Singapore
  • eBook Packages Medicine
  • Print ISBN 978-981-10-6576-7
  • Online ISBN 978-981-10-6577-4
  • Buy this book on publisher's site