Molecular Diagnosis and Targeting for Thoracic and Gastrointestinal Malignancy

  • Yutaka Shimada
  • Katsuhiko Yanaga

Part of the Current Human Cell Research and Applications book series (CHCRA)

Table of contents

  1. Front Matter
    Pages i-viii
  2. Kazue Yoneda, Fumihiro Tanaka
    Pages 1-32
  3. Akira Tangoku, Takahiro Yoshida, Hirokazu Takechi, Masakazu Okumua, Misako Nakagawa, Masami Morimoto et al.
    Pages 33-47
  4. Tomoyuki Okumura, Hirohumi Kojima, Tetsuji Yamaguchi, Yutaka Shimada
    Pages 49-62
  5. Nobuhisa Matsuhashi, Kazuhiro Yoshida, Kazuya Yamaguchi, Toshiyuki Tanahashi
    Pages 63-80
  6. Ken Takahashi, Hiroyuki Marusawa
    Pages 93-110
  7. Kazuhiro Hanazaki, Masaya Munekage, Hiroyuki Kitagawa, Takuhiro Kosaki, Toshiji Saibara, Tsutomu Namikawa
    Pages 111-125
  8. Izumi Komoto, Yohei Hosoda, Masayuki Imamura
    Pages 145-156

About this book


This volume focuses on the clinical applications of molecular diagnosis and targeted therapy from the viewpoint of oncologists specializing in specific organs. In addition, it discusses the role of molecular diagnosis and targeted therapy in the course of surgical treatment.

Recent, rapid advances in molecular biology have shed new light on the mechanisms of cancer progression, and molecularly targeted drugs have been used to treat a variety of malignant diseases. For the diagnosis and precise treatment of cancer, analysis of the molecular background of the tumor is indispensable. However, there are both tumor-specific and comprehensive mechanisms involved in these processes. Accordingly, a firm grasp of molecular diagnosis and targeted therapies for different tumors is vital for clinicians and basic researchers alike.

This book provides essential information and the latest findings on molecular diagnosis and targeted therapy for thoracic and gastrointestinal malignancies. Though primarily intended for clinical and basic oncologists, it also offers a useful guide for clinicians who are interested in this field and are considering getting started in molecular diagnosis and targeted therapy.


Molecular diagnosis Targeted therapy Stem cell biology Breast cancer Lung Cancer Esophageal cancer Gastric cancer Colorectal cancer Hepatocellular carcinoma Biliary tract cancer Pancreatic cancer Neuroendocrine tumors

Editors and affiliations

  • Yutaka Shimada
    • 1
  • Katsuhiko Yanaga
    • 2
  1. 1.Department of Nanobio Drug DiscoveryKyoto UniversitySakyo-kuJapan
  2. 2.Department of SurgeryJikei University School of MedicineMinato-kuJapan

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2018
  • Publisher Name Springer, Singapore
  • eBook Packages Medicine
  • Print ISBN 978-981-10-6468-5
  • Online ISBN 978-981-10-6469-2
  • Series Print ISSN 2522-073X
  • Series Online ISSN 2522-0748
  • Buy this book on publisher's site