Lymph Node Metastasis in Gastrointestinal Cancer

  • Shoji¬†Natsugoe

Table of contents

  1. Front Matter
    Pages i-viii
  2. Toshio Ohhashi, Yoshiko Kawai
    Pages 1-16
  3. Tatsuo Sato
    Pages 17-67
  4. Naohide Oue, Yasuhiko Kitadai, Wataru Yasui
    Pages 69-92
  5. Basic Science of the Lymphatic System

    1. Front Matter
      Pages 93-93
    2. Ryota Hokari, Soichiro Miura
      Pages 95-110
    3. Takahiro Nagatake, Jun Kunisawa, Hiroshi Kiyono
      Pages 111-126
    4. Kazunobu Ohnuki, Hirofumi Fujii
      Pages 127-157
    5. Takeshi Imamura, Takashi Saitou, Sota Takanezawa, Ryosuke Kawakami
      Pages 159-176
  6. Lymph Node Micrometastasis

    1. Front Matter
      Pages 177-177
    2. Shuhei Ito, Takaaki Masuda, Yosuke Kuroda, Hidetoshi Eguchi, Koshi Mimori
      Pages 179-193
    3. Itaru Omoto, Yasuto Uchikado, Ken Sasaki, Takaaki Arigami, Shoji Natsugoe
      Pages 195-207
    4. Takaaki Arigami, Yoshikazu Uenosono, Shigehiro Yanagita, Sumiya Ishigami, Shoji Natsugoe
      Pages 209-223
    5. Hirofumi Yamamoto, Masaki Mori
      Pages 225-236
    6. Yoshiaki Kajiyama, Natsumi Tomita, Takashi Hashimoto
      Pages 249-263
  7. Lymph Node Metastasis: Clinical Significance

    1. Front Matter
      Pages 265-265
    2. Koshi Kumagai, Takeshi Sano
      Pages 267-282
    3. Kazushige Kawai, Kensuke Otani, Manabu Kaneko, Koji Murono, Kazuhito Sasaki, Toshiaki Watanabe
      Pages 283-302
  8. Sentinel Node Navigation Surgery

    1. Front Matter
      Pages 303-303
    2. Shinichi Kinami, Takeo Kosaka
      Pages 305-321
    3. Akira Tangoku, Takahiro Yoshida, Hiroaki Toba, Hirokazu Takechi, Masakazu Okumua, Takeshi Nishino et al.
      Pages 323-333
    4. Yoshikazu Uenosono, Takaaki Arigami, Shigehiro Yanagita, Itaru Omoto, Ken Sasaki, Yasuto Uchikado et al.
      Pages 335-346
    5. Hiroya Takeuchi, Yuko Kitagawa
      Pages 347-358

About this book


This book provides the most comprehensive and up-to-date knowledge of lymph node micrometastasis (LMM) and sentinel node navigation surgery (SNNS) in gastrointestinal cancers.

Lymph node metastasis is a critically important prognostic factor in gastrointestinal tract cancers such as tumors of the esophagus, stomach, and colorectum. An understanding of the basic aspects of lymphatics and lymph nodes, including anatomy, histology, physiology, immunology, and molecular biology, is fundamental for physicians who are involved in cancer treatment. Furthermore, owing to the development of molecular and biological methodology, the precise recognition of LMM and its clinical significance have been clarified recently.

At the same time, SNNS has actually been anticipated in treatment of breast tumors, and it is now being introduced in gastrointestinal tract cancer. For the application of SNNS, the detection of lymph node metastasis including LMM is extremely significant, because the presence of LMM determines the direction for surgery and chemo and/or radiation therapy.

With these considerations in mind, the expert contributors to this book review basic and clinical approaches for LMM and SNNS including methodology for gastrointestinal cancers. Thus this volume benefits not only surgeons who treat gastrointestinal cancers but also clinical oncologists and medical scientists such as physiologists and pathologists.


Sentinel node navigation surgery Esophageal cancer Gastric cancer Colorectal cancer Cancer treatment. Lymphatic Chemotherapy Radiation therapy

Editors and affiliations

  • Shoji¬†Natsugoe
    • 1
  1. 1.Department of Digestive Surgery, Breast and Thyroid SurgeryKagoshimaJapan

Bibliographic information

  • DOI
  • Copyright Information Springer Nature Singapore Pte Ltd. 2019
  • Publisher Name Springer, Singapore
  • eBook Packages Medicine
  • Print ISBN 978-981-10-4698-8
  • Online ISBN 978-981-10-4699-5
  • Buy this book on publisher's site