Fundamentals of MALDI-ToF-MS Analysis

Applications in Bio-diagnosis, Tissue Engineering and Drug Delivery

  • Samira Hosseini
  • Sergio O. Martinez-Chapa

Part of the SpringerBriefs in Applied Sciences and Technology book series (BRIEFSAPPLSCIENCES)

Also part of the Springer Briefs in Forensic and Medical Bioinformatics book sub series (BRIEFSFOMEBI)

Table of contents

  1. Front Matter
    Pages i-xi
  2. Samira Hosseini, Sergio O. Martinez-Chapa
    Pages 1-19
  3. Samira Hosseini, Sergio O. Martinez-Chapa
    Pages 21-39
  4. Back Matter
    Pages 67-68

About this book


This book presents the fundamentals and applications of Matrix Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-ToF-MS) technique. It highlights the basic principles, the history of invention as well as the mechanism of ionization and mass determination using this technique. It describes the fundamental principles and methods for MALDI spectra interpretation and determination of exact chemical structures from experimental data. This book guides the reader through the interpretation of MALDI data where complex macromolecular spectra are simplified in order to present the major principles behind data interpretation. In addition, each chapter describes how MALDI-ToF-MS analysis provides necessary understanding of the copolymer systems that have been designed for specialized biomedical applications.


Time of Flight Mass Spectrometry Laser Range in MALDI Dried-droplet Analysis Electrospray Deposition Ionizing Agent Selection Fourier Transform Ion Cyclotron Resonance (FT-ICR) Size Exclusion Chromatograph (SEC) Tin Layer Chromatography (TLC) Synthesis of PMMA Elastomeric Films and Coatings

Authors and affiliations

  • Samira Hosseini
    • 1
  • Sergio O. Martinez-Chapa
    • 2
  1. 1.School of Engineering and SciencesTecnológico de Monterrey School of Engineering and SciencesMonterreyMexico
  2. 2.School of Engineering and SciencesTecnológico de Monterrey School of Engineering and SciencesMonterreyMexico

Bibliographic information

  • DOI
  • Copyright Information The Author(s) 2017
  • Publisher Name Springer, Singapore
  • eBook Packages Engineering Engineering (R0)
  • Print ISBN 978-981-10-2355-2
  • Online ISBN 978-981-10-2356-9
  • Series Print ISSN 2191-530X
  • Series Online ISSN 2191-5318
  • Buy this book on publisher's site