Stress Response Pathways in Cancer

From Molecular Targets to Novel Therapeutics

  • Georg T. Wondrak

Table of contents

  1. Front Matter
    Pages i-xii
  2. Loredana Spoerri, Zay Yar Oo, Jill E. Larsen, Nikolas K. Haass, Brian Gabrielli, Sandra Pavey
    Pages 29-49
  3. Núria Sima, Laia Bosch-Presegué, Alejandro Vaquero
    Pages 75-106
  4. Haoran Li, Shaan Gupta, Burton B. Yang
    Pages 107-126
  5. Sandra Muñoz-Galvan, Amancio Carnero
    Pages 127-155
  6. Madhuri Kalathur, Diletta Di Mitri, Andrea Alimonti
    Pages 157-182
  7. Anna Budina-Kolomets, Subhasree Basu, Lili Belcastro, Maureen E. Murphy
    Pages 203-224
  8. Lydia Mata-Cantero, Sofía Lobato-Gil, Fabienne Aillet, Valérie Lang, Manuel S. Rodriguez
    Pages 225-264
  9. Varda Shoshan-Barmatz, Anna Shteinfer, Danya Ben-Hail, Tasleem Arif, Dario Mizrachi
    Pages 345-373
  10. Colin W. Steele, Nigel B. Jamieson, C. Ross Carter
    Pages 375-395
  11. Jeffrey J. Rodvold, Navin R. Mahadevan, Maurizio Zanetti
    Pages 397-429
  12. Back Matter
    Pages 431-446

About this book


It is now established that dysregulated cell stress response pathways play a critical role in tumorigenesis, and a refined mechanistic understanding of this phenomenon at the molecular level promises to open new avenues for targeted therapeutic strategies that may benefit cancer patients in the near future. Coauthored by recognized leaders in cancer research from five continents, this novel book provides a comprehensive perspective on cell stress response pathways and therapeutic opportunities. Focusing on the role of genotoxic, proteotoxic, oxidative, metabolic, and inflammatory stress in tumorigenesis, the book is essential reading for students, basic researchers, and biomedical health care professionals interested in cancer and therapeutic development.


cancer biology cell stress response drug discovery and therapeutic development heat shock response redox dysregulation

Editors and affiliations

  • Georg T. Wondrak
    • 1
  1. 1.Dept. of Pharmacology and ToxicologyUniv. of Arizona, College of Pharm. & The Univ. of Arizona Cancer Ctr.TucsonUSA

Bibliographic information