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Synthetic Biology

From iGEM to the Artificial Cell

  • Manuel Porcar
  • Juli Peretó

Part of the SpringerBriefs in Biochemistry and Molecular Biology book series (BRIEFSBIOCHEM, volume 12)

Table of contents

  1. Front Matter
    Pages i-xii
  2. Manuel Porcar, Juli Peretó
    Pages 1-7
  3. Manuel Porcar, Juli Peretό
    Pages 9-22
  4. Manuel Porcar, Juli Peretó
    Pages 23-32
  5. Manuel Porcar, Juli Peretó
    Pages 33-44
  6. Manuel Porcar, Juli Peretó
    Pages 45-53
  7. Manuel Porcar, Juli Peretó
    Pages 55-62
  8. Manuel Porcar, Juli Peretó
    Pages 63-68
  9. Back Matter
    Pages 69-77

About this book

Introduction

Synthetic Biology (SB) is a revolutionary discipline with a vast range of practical applications, but is SB research really based on engineering principles? Does it contributing to the artificial synthesis of life or does it utilise approaches sufficiently advanced to fall outside the scope of biotechnology or metabolic engineering? This volume reviews the development of SB and includes the major milestones of the discipline, the ‘top-down’ and ‘bottom-up’ approaches towards the construction of an artificial cell and the development of the “iGEM” competition. We conclude that SB is an emerging field with extraordinary technological potential, but that most research projects actually are an extension of metabolic engineering since the complexity of living organisms, their tight dependence on evolution and our limited knowledge of the interactions between the molecules, actually make life difficult to engineer.

Keywords

artificial life biotechnology metabolic engineering minimal cell synthetic biology

Authors and affiliations

  • Manuel Porcar
    • 1
  • Juli Peretó
    • 2
  1. 1.General Foundation and Cavanilles Institute for Biodiversity and Evolutionary BiologyUniversity of ValenciaPaternaSpain
  2. 2.Department of Biochemistry and Molecular Biology and Cavanilles Institute for Biodiversity and Evolutionary BiologyUniversity of ValenciaPaternaSpain

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-017-9382-7
  • Copyright Information The Author(s) 2014
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-94-017-9381-0
  • Online ISBN 978-94-017-9382-7
  • Series Print ISSN 2211-9353
  • Series Online ISSN 2211-9361
  • Buy this book on publisher's site