Stem Cells and Cancer Stem Cells, Volume 12

Therapeutic Applications in Disease and Injury

  • M.A. Hayat

Part of the Stem Cells and Cancer Stem Cells book series (STEM, volume 12)

Table of contents

  1. Front Matter
    Pages i-xlii
  2. Cancer Stem Cells

    1. Front Matter
      Pages 1-1
    2. Maria Francisca Eiriz, João Oliveira Malva, Fabienne Agasse, Liliana Bernardino
      Pages 3-17
    3. Joanne L. Van der Velden, Ivan Bertoncello, Jonathan L. McQualter
      Pages 19-26
  3. Pluripotent Stem Cells

  4. Dendritic Cells

  5. Regenerative Medicine

    1. Front Matter
      Pages 129-129
    2. Alfonso Eirin, Behzad Ebrahimi, Lilach O. Lerman
      Pages 143-150
    3. Manuel Picón-Ruiz, Salvatore Pernagallo, Juan José Díaz-Mochón, Cynthia Morata, Macarena Perán, Juan Antonio Marchal
      Pages 151-164
    4. Hiroshi Mizuno, Morikuni Tobita, Hakan Orbay, A. Cagri Uysal, Feng Lu
      Pages 165-174
  6. General Applications

    1. Front Matter
      Pages 187-187
    2. Antonio Díaz-López, Amparo Cano
      Pages 189-199
    3. Wayne M. Eby, Mohammad A. Tabatabai
      Pages 201-217
    4. Antonella Poloni, Giulia Maurizi
      Pages 231-240
    5. Folker Wenzel
      Pages 241-245
  7. Back Matter
    Pages 247-256

About this book


Volume 12 in this series explores the latest experimental and clinical uses of stem cells in the treatment of disease and of injuries and reviews methods for isolating multipotent endothelial-like cells from human adipose tissue and discusses clinical applications in cell therapy and regenerative medicine.


The book is organized in five parts: Cancer Stem Cells, Pluripotent Stem Cells, Dendritic Stem Cells, Regenerative Medicine and General Applications. The first section includes chapters on histamine in the neural and cancer stem cell niches, and emerging concepts of stem cell organization in the normal lung and in lung cancer. The section on Pluripotent Stem Cells includes discussion of the differentiation of dendritic cells from human induced pluripotent stem cell and the molecular mechanisms involved in reprogramming human somatic cells to generate induced pluripotent stem cells. Additional chapters cover the differentiation of induced pluripotent stem cells into functional cardiomyocytes, characteristics of satellite cells and multipotent adult stem cells in the skeletal muscle. The section on Dendritic Stem Cells explores the critical role of notch signaling in the differentiation and function of dendrite. Other chapters cover hypertensive emergencies in children after stem cell

transplantation, and overcoming the radio resistance of lung cancer stem cells. The section on Regenerative Medicine reports on experiments on improved renal revascularization in pigs using stem cells and phenotypic correction of murine Hemophilia A using cell-based therapy. The concluding section, General Applications, discusses such topics as methods in mathematical modeling for stem cells, as well as molecular and functional characterization of human adipocytes.


Like its eleven predecessors in the series, this volume stands out for its comprehensive approach, its roster of some 51 expert contributors representing a dozen different countries and its up-to-date review of leading-edge technology and methods.


Cancer therapy Graft-versus host disease Hemophilia treatment Isolation of stem cells Tissue regeneration

Editors and affiliations

  • M.A. Hayat
    • 1
  1. 1.Department of Biological SciencesKean University, Room 213, Library BuildingUnionUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media Dordrecht 2014
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-94-017-8031-5
  • Online ISBN 978-94-017-8032-2
  • Series Print ISSN 2215-0994
  • Series Online ISSN 2215-1001
  • Buy this book on publisher's site