Cytochrome Complexes: Evolution, Structures, Energy Transduction, and Signaling

  • William A. Cramer
  • Toivo Kallas

Part of the Advances in Photosynthesis and Respiration book series (AIPH, volume 41)

Table of contents

  1. Front Matter
    Pages i-xlv
  2. Diversity and Evolution

    1. Front Matter
      Pages 1-1
    2. Derek S. Bendall
      Pages 3-11
    3. Erica L.-W. Majumder, Robert E. Blankenship
      Pages 25-50
  3. Theoretical Aspects of Electron Transfer

    1. Front Matter
      Pages 71-71
    2. Lev I. Krishtalik
      Pages 73-98
  4. Molecular Structures and Functions of Cytochrome Complexes

    1. Front Matter
      Pages 129-129
    2. Frank Müh, Athina Zouni
      Pages 143-175
    3. William A. Cramer, S. Saif Hasan
      Pages 177-207
    4. Marcin Sarewicz, Robert Ekiert, Artur Osyczka
      Pages 281-294
    5. Joseph A. Lyons, Florian Hilbers, Martin Caffrey
      Pages 307-329
    6. Shinya Yoshikawa
      Pages 357-373
    7. Luke Young, Benjamin May, Tomoo Shiba, Shigeharu Harada, Daniel Ken Inaoka, Kiyoshi Kita et al.
      Pages 375-394
  5. Superoxide Generation in Cytochrome bc Complexes

    1. Front Matter
      Pages 395-395
    2. Danas Baniulis, S. Saif Hasan, Inga Miliute, William A. Cramer
      Pages 397-417
  6. Cytochrome Complexes, Signaling, and Regulation

    1. Front Matter
      Pages 435-435
    2. Sébastien Zappa, Carl E. Bauer
      Pages 479-498
  7. Assembly of Cytochrome Complexes and Super-Complexes

    1. Front Matter
      Pages 499-499
    2. Sara Guenthner Cline, Stéphane Thierry Gabilly, Nitya Subrahmanian, Patrice Paul Hamel
      Pages 501-525
    3. Bahia Khalfaoui-Hassani, Andreia F. Verissimo, Namita P. Shroff, Seda Ekici, Petru-Iulian Trasnea, Marcel Utz et al.
      Pages 527-554
    4. Hans-Georg Koch, Dirk Schneider
      Pages 555-584
    5. Giorgio Lenaz, Maria Luisa Genova
      Pages 585-628
  8. Branched Pathways and Cryptic Cytochromes

    1. Front Matter
      Pages 629-629
    2. Derek S. Bendall, Christopher J. Howe
      Pages 631-655
    3. Irene Díaz-Moreno, Antonio Díaz-Quintana, Miguel A. De la Rosa
      Pages 657-677
    4. Melanie A. Spero, Saheed Imam, Daniel R. Noguera, Timothy J. Donohue
      Pages 679-700
    5. Christopher J. Howe, Robert H. Nimmo, Adrian C. Barbrook, Derek S. Bendall
      Pages 701-712
    6. Wojciech Bialek, Andrzej Szczepaniak, Piotr Kolesinski, Toivo Kallas
      Pages 713-734
  9. Back Matter
    Pages 735-739

About this book


Why study cytochrome complexes?  An answer is in the subtitle of the book “Evolution, Structures, Energy Transduction, and Signaling”. Studies on the cytochrome family of proteins include and, influence, a wide range of theoretical and computational approaches, as well as a broad cross-section of experimental techniques. Studies of cytochromes and cytochrome complexes thus utilize an extraordinary range of experimental approaches, described in this volume, which include: computational biology, genetics, macromolecular biochemistry, molecular biology, the physics of charge transfer, structure analysis using x-ray and electron diffraction, and ultra-fast spectroscopy. This information and understanding exerts an influence on a wide spectrum of subjects in modern biology, including molecular evolution, mechanisms of membrane-based respiratory and photosynthetic energy transduction, theory of charge transfer in proteins, structure-function of large hetero-oligomeric membrane proteins, including lipid-protein interactions, and trans-membrane signaling.

The book starts with a historical introduction that focuses on research in the first half of the 20th century, and the pre-World War II development in England of the field and its notation, proceeding to a discussion of the evolution of cytochromes and hemes, fundamentals of the theory of electron transfer in proteins, and an extensive description of molecular structures of cytochromes and of the cytochrome complexes. The latter information has had a major impact on the broad field of the structure-function of integral membrane proteins, the newest area of macromolecular structural biology. The book includes thorough discussions on cytochrome oxidase including the use of the new non-destructive femtosecond “diffraction before destruction” X-ray free electron laser for diffraction analysis, and major sections on signaling, super-complexes, state transitions, and the interaction of linear and cyclic electron transport chains.

The extent of fundamental research areas included in this book makes it an important resource for the teaching of broad aspects of biological energy transduction to advanced undergraduate and graduate students with interests in biology, biochemistry, biological engineering, chemistry, and biophysics.


Cytochromes Energy transduction Membranes Evolution Signaling

Editors and affiliations

  • William A. Cramer
    • 1
  • Toivo Kallas
    • 2
  1. 1.Department of Biological SciencesPurdue UniversityWest LafayetteUSA
  2. 2.Department of BiologyUniversity of Wisconsin-OshkoshOshkoshUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media Dordrecht 2016
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-94-017-7479-6
  • Online ISBN 978-94-017-7481-9
  • Series Print ISSN 1572-0233
  • Series Online ISSN 2215-0102
  • Buy this book on publisher's site