Non-coding RNA and the Reproductive System

  • Dagmar Wilhelm
  • Pascal Bernard

Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 886)

Table of contents

  1. Front Matter
    Pages i-vii
  2. Andrew Pask
    Pages 1-12
  3. Jennifer X. Yang, Raphael H. Rastetter, Dagmar Wilhelm
    Pages 13-32
  4. Jean-François Ouimette, Claire Rougeulle
    Pages 33-49
  5. Katalin Fejes Tóth, Dubravka Pezic, Evelyn Stuwe, Alexandre Webster
    Pages 51-77
  6. J. Browning Fitzgerald, Jitu George, Lane K. Christenson
    Pages 79-93
  7. J. E. Holt, S. J. Stanger, B. Nixon, E. A. McLaughlin
    Pages 95-120
  8. Gurveen K. Sandhu, Michael J. G. Milevskiy, Wesley Wilson, Annette M. Shewan, Melissa A. Brown
    Pages 121-153
  9. Back Matter
    Pages 191-198

About this book

Introduction

This book provides an overview of the role and function of regulatory RNAs that lack protein-coding potential in key reproductive tissues. This includes the role of small interfering RNAs (siRNAs), microRNAs (miRNAs), PIWI-interacting RNAs (piRNAs), small nucleolar RNAs (snoRNAs) and long non-coding RNAs (lncRNAs). Through clear, detailed and comprehensive debate, international leading experts discuss the role these novel regulators in normal development of sexual dimorphisms, including the differentiation of ovaries and testes, the genital tract including prostate, epididymis and uterus, as well as mammary glands. In addition, particular attention is paid on their role in pathophysiological processes within the reproductive tract.

The power of next generation sequencing has proved to be an invaluable tool to discover new non-coding RNAs. While the identification of non-coding RNA is relatively easy, analysing their function represents still a challenge today. In this book, authors present historical and conceptual background information, highlight the ways in which non-coding RNAs function is analysed and present their vision of the future research in their key research area.

Keywords

diseases of the reproductive system gene regulation non-coding RNA reproduction sex differentiation

Editors and affiliations

  • Dagmar Wilhelm
    • 1
  • Pascal Bernard
    • 2
  1. 1.Department of Anatomy and NeuroscienceThe University of Melbourne Department of Anatomy and NeuroscienceParkvilleAustralia
  2. 2.School of BioSciencesThe University of Melbourne School of BioSciencesMelbourneAustralia

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-017-7417-8
  • Copyright Information Springer Science+Business Media Dordrecht 2016
  • Publisher Name Springer, Dordrecht
  • eBook Packages Biomedical and Life Sciences
  • Print ISBN 978-94-017-7415-4
  • Online ISBN 978-94-017-7417-8
  • Series Print ISSN 0065-2598
  • Series Online ISSN 2214-8019
  • About this book