AIDS Pathogenesis

  • Hanneke Schuitemaker
  • Frank Miedema

Part of the Immunology and Medicine Series book series (IMME, volume 28)

Table of contents

  1. Front Matter
    Pages I-XI
  2. Angélique Van’t Wout, Richard A. Koup, William A. Paxton
    Pages 1-17
  3. Andrew Carr, David A. Cooper
    Pages 19-40
  4. Jan Albert, Maarten Koot
    Pages 41-54
  5. Dawn R. Clark, Katja C. Wolthers
    Pages 55-64
  6. Susan Buchbinder, Eric Vittinghoff
    Pages 65-75
  7. M. R. Klein, S. H. Van der Burg, B. Autran
    Pages 77-98
  8. Paul W. H. I. Parren, Dennis R. Burton, Quentin J. Sattentau
    Pages 99-132
  9. Jannik Helweg-Larsen, Thomas L. Benfield, Jens D. Lundgren
    Pages 155-176
  10. Marie José Kersten, M. H. J. Van Oers
    Pages 177-194
  11. Thomas F. Schulz
    Pages 195-208
  12. Peter Portegies, Roelien H. Enting
    Pages 209-220
  13. Joep M. A. Lange, Julio S. G. Montaner
    Pages 221-242
  14. Marijke Th. L. Roos, Nadine G. Pakker, Peter Th. A. Schellekens
    Pages 243-259
  15. Frank De Wolf, Ingrid Spijkerman
    Pages 261-272
  16. Back Matter
    Pages 283-283

About this book


Infection with the human immunodeficiency virus is characterized by the destruction of the host immune system as also reflected by a progressive loss of CD4-positive T-cells. This finally results in the host's incapacity to deal with opportunistic infections and the immune surveillance of tumors, a clinical status known as the Acquired Immunodeficiency Syndrome (AIDS).
The book AIDS Pathogenesis provides the reader with a complete overview of the clinical course of HIV-1 infection. It describes the clinical aspects of primary infection, the different clinical outcomes of HIV-1 infection, and strategies for anti-viral treatment. In addition, more fundamental aspects of HIV-1 infection are reviewed. These include the biology of the virus and the novel insights in AIDS pathogenesis. Not only is the significance of an HIV-specific cellular and humoral immune response discussed, but also the possible incapacity of the adult human host to deal with T-cell destruction. Finally, the book discusses the currently used laboratory markers that allow for monitoring of the clinical course of infection.


AIDS HIV HIV infection infection infections therapy virus

Editors and affiliations

  • Hanneke Schuitemaker
    • 1
  • Frank Miedema
    • 1
  1. 1.CLB and Laboratory for Experimental and Clinical ImmunologyUniversity of AmsterdamAmsterdamThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 2000
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-90-481-5407-4
  • Online ISBN 978-94-017-0685-8
  • Buy this book on publisher's site