Aging of Cells in and Outside the Body

  • Sunil C. Kaul
  • Renu Wadhwa

Part of the Biology of Aging and its Modulation book series (BIMO, volume 2)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Olivia M. Pereira-Smith, Paul Rookard, Johanna Echigo, James R. Smith
    Pages 9-26
  3. Dimitris Kletsas
    Pages 27-46
  4. Tsutomu Kumazaki
    Pages 47-65
  5. Moustapha Kassem, Karin Stenderup, Jeannette Justesen, Marie Kveiborg
    Pages 67-84
  6. Graham Pawelec
    Pages 85-100
  7. Jan O. Nehlin
    Pages 101-119
  8. Antony W. Braithwaite, Sara J. Edwards
    Pages 121-149
  9. Therese M. Becker, Helen Rizos
    Pages 151-169
  10. Christian D. Toouli, Roger R. Reddel
    Pages 171-205
  11. Geneviève Morrow, Robert M. Tanguay
    Pages 207-223
  12. Renu Wadhwa, Md. Kamrul Hasan, Sunil C. Kaul
    Pages 225-238
  13. Hiroshi Minoshima, Eigo Suyama, Renu Wadhwa, Kazunari Taira
    Pages 257-267
  14. Back Matter
    Pages 269-276

About this book


This book provides updated knowledge on the basic features and mechanisms of cellular aging established since its first manifestation at cellular level 40 years ago. Contributions of genetic and environmental factors, failure of genetic and cellular repair mechanisms, and the epigenetic modifications determine the final lifespan of cells. This book also provides an understanding on how aging mechanisms in mice, a most frequently used model, differ with that of humans who receive better tumor surveillance because of stringent controls on aging mechanisms. It also appraises the use of modern technology for aging studies and its intervention. This book serves as an excellent reading on cellular aging for undergraduate students, researchers and experts of this area.


Chaperone aging mouse regulation senescence tumor surveillance

Editors and affiliations

  • Sunil C. Kaul
    • 1
  • Renu Wadhwa
    • 1
  1. 1.National Institute of Advanced Industrial, Science and TechnologyTsukuba Science CityIbarakiJapan

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media Dordrecht 2003
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-90-481-6314-4
  • Online ISBN 978-94-017-0669-8
  • Buy this book on publisher's site