© 1995

Risk Assessment of Chemicals

An Introduction

  • C. J. van Leeuwen
  • J. L. M. Hermens

Table of contents

  1. Front Matter
    Pages i-xviii
  2. C. J. van Leeuwen
    Pages 1-17
  3. P. Van Der Poel, J. P. M. Ros
    Pages 19-36
  4. M. Van Den Berg, D. Van De Meent, W. J. G. M. Peijnenburg, D. T. H. M. Sijm, J. Struijs, J. W. Tas
    Pages 37-102
  5. D. Van De Meent, J. H. M. De Bruijn, F. A. A. M. De Leeuw, A. C. M. De Nijs, D. T. Jager, T. G. Vermeire
    Pages 103-145
  6. R. Kroes
    Pages 147-174
  7. C. J. Van Leeuwen
    Pages 175-237
  8. M. Nendza, J. Hermens
    Pages 239-292
  9. T. Vermeire, P. Van Der Zandt
    Pages 293-337
  10. Back Matter
    Pages 339-374

About this book


In recent years many developments have taken place in promote co-operation between governments and other the field of risk assessment of chemicals. Many reports parties involved in chemical safety and to provide policy have been published by national authorities, industries guidance with emphasis on regional and subregional co­ and scientific researchers as well as by international bod­ operation. The Inter-Organization Programme for the ies such as the European Union, the Organization of Sound Management of Chemicals (IOMC) was estab­ Economic Cooperation and Development (OECD) and lished in 1995 and provides a mechanism for the six par­ the joint International Programme on Chemical Safety ticipating organizations (UNEP, ILO, FAO, UNIDO,WHO (IPCS) of the World Health Organization (WHO), the and OECD) to better co-ordinate policies and activities in International Labour Organization (lLO), and the United the field of chemical risk management. Nations Environment Programme (UNEP). The present book is an introduction to risk assessment of The development and international harmonization of risk chemicals. It contains basic background information on assessment methods is an important challenge. In sources, emissions, distribution and fate processes for Agenda 21 of the United Nations Conference on exposure estimation. It includes dose-effects estimation Environment and Development (UNCED), chapter 19 is for both human health related toxicology and ecotoxicol­ entirely devoted to the management of chemicals. For ogy as well as information on estimation methodologies. one of its recommendations, i. e.


Biotransformation development environment soil toxicity toxicology

Editors and affiliations

  • C. J. van Leeuwen
    • 1
  • J. L. M. Hermens
    • 2
  1. 1.Ministry of Housing, Spatial Planning and Environment, The Hague & Research Institute of ToxicologyUniversity of UtrechtThe Netherlands
  2. 2.Research Institute of ToxicologyUniversity of UtrechtThe Netherlands

Bibliographic information


` ... takes an interesting and forward-looking point of view. The book is an excellent, high-level textbook. It is well written and has a clear layout ... which varies sufficiently to make reading easy. ... essential reading material for students of environmental sciences and it should be strongly recommended to engineers. Because of the forward-looking nature of its scientific content, it will be of substantial support to professional environmental managers for years to come.'
International Journal of Environment/Pollution, 8:1-2 (1998)