Methodology for Genetic Studies of Twins and Families

  • Michael C. Neale
  • Lon R. Cardon
Part of the NATO ASI Series book series (ASID, volume 67)

Table of contents

  1. Front Matter
    Pages i-xxv
  2. Michael C. Neale, Lon R. Cardon
    Pages 1-33
  3. Michael C. Neale, Lon R. Cardon
    Pages 35-53
  4. Michael C. Neale, Lon R. Cardon
    Pages 55-70
  5. Michael C. Neale, Lon R. Cardon
    Pages 71-86
  6. Michael C. Neale, Lon R. Cardon
    Pages 87-108
  7. Michael C. Neale, Lon R. Cardon
    Pages 109-130
  8. Michael C. Neale, Lon R. Cardon
    Pages 131-148
  9. Michael C. Neale, Lon R. Cardon
    Pages 149-187
  10. Michael C. Neale, Lon R. Cardon
    Pages 189-197
  11. Michael C. Neale, Lon R. Cardon
    Pages 199-210
  12. Michael C. Neale, Lon R. Cardon
    Pages 211-229
  13. Michael C. Neale, Lon R. Cardon
    Pages 231-259
  14. Michael C. Neale, Lon R. Cardon
    Pages 261-287
  15. Michael C. Neale, Lon R. Cardon
    Pages 289-304
  16. Michael C. Neale, Lon R. Cardon
    Pages 305-311
  17. Michael C. Neale, Lon R. Cardon
    Pages 313-327
  18. Michael C. Neale, Lon R. Cardon
    Pages 329-351
  19. Michael C. Neale, Lon R. Cardon
    Pages 353-372
  20. Back Matter
    Pages 373-496

About this book

Introduction

Few would dispute the truth of the statement `People are Different', but there is much controversy over why. This book authoritatively explains the methods used to understand human variation, and extends them far beyond the primary `nature or nurture' question. After chapters on basic statistics, biometrical genetics, matrix algebra and path analysis, there is a state-of-the-art account of how to fit genetic models using the LISREL package.
The authors explain not only the assumptions of the twin method, but how to test them. The elementary model is expanded to cover sex limitation, sibling interaction, multivariate and longitudinal data, observer ratings, and twin-family studies. Throughout, the methods are illustrated by applications to diverse areas such as obesity, major depression, alcohol comsumption, delinquency, allergies, and common fears.

Keywords

alcohol allergy depression genetics methodology obesity sex statistics

Authors and affiliations

  • Michael C. Neale
    • 1
  • Lon R. Cardon
    • 2
  1. 1.Department of Human Genetics, Medical College of VirginiaVirginia Commonwealth UniversityRichmondUSA
  2. 2.Institute for Behavioral GeneticsUniversity of ColoradoBoulderUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-015-8018-2
  • Copyright Information Springer Science+Business Media B.V. 1992
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-90-481-4179-1
  • Online ISBN 978-94-015-8018-2
  • Series Print ISSN 0258-123X
  • About this book