Risk-Benefit Analysis in Drug Research

Proceedings of an International Symposium held at the University of Kent at Canterbury, England, 27 March 1980

  • J. F. Cavalla

Table of contents

  1. Front Matter
    Pages i-x
  2. Edward E. Pochin
    Pages 1-16
  3. B. B. Newbould
    Pages 17-25
  4. J. Maddox, J. Coombes
    Pages 27-42
  5. D. Ennals
    Pages 43-49
  6. D. G. Grahame-Smith, J. Coombes
    Pages 51-66
  7. C. N. Christensen
    Pages 67-73
  8. A. M. Breckenridge, T. I. Wrigley
    Pages 75-92
  9. P. A. J. Janssen
    Pages 93-95
  10. A. D. Dayan
    Pages 97-112
  11. J. D. Spink, T. I. Wrigley
    Pages 113-130
  12. J. F. Dunne
    Pages 131-134
  13. R. W. Brimblecombe
    Pages 135-140
  14. W. H. W. Inman, C. T. Dollery
    Pages 141-161
  15. S. Lock, C. T. Dollery
    Pages 163-177
  16. Douglas Black
    Pages 179-184
  17. C. T. Dollery
    Pages 185-190
  18. Back Matter
    Pages 191-197

About this book


The appreciation of risk like the awareness of beauty lies very much in the eyes of the beholder. It involves a value judgement and can never be absolute. Yet paradoxically, modern society is demanding ever greater degrees of safety in the medicines it takes, to the extent that nothing short of the total absence of risk will be tolerated. Since 1960, and mainly as a result of the thalidomide tragedy, governmental regulation of testing and use of new medicines has grown apace throughout the world. It has derived impetus not only from the understandable wish of the public to seek protection, but also from the anxiety of bureaucrats and politicians not to be seen to have made mistakes. Both these concerns have been inflamed by the recognition of the media that all drugs make news and horror drugs make the best news of all. Prior to this time the physician and his cures enjoyed a relatively supportive public. It was true that quacks existed and were recognized as such but, in the main, people wanted to take medicines and expected them to do them good.


drug drug research research

Editors and affiliations

  • J. F. Cavalla
    • 1
  1. 1.Wyeth LaboratoriesTaplow, Maidenhead, BerkshireEngland

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1981
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-015-7134-0
  • Online ISBN 978-94-015-7132-6
  • Buy this book on publisher's site