Herpesvirus DNA

Recent studies on the organization of viral genomes, mRNA transcription, DNA replication, defective DNA, and viral DNA sequences in transformed cells and bacterial plasmids

  • Yechiel Becker

Part of the Developments in Molecular Virology book series (DMVI, volume 1)

Table of contents

  1. Front Matter
    Pages I-XIV
  2. Introduction: Current trends in herpesvirus DNA research (a review)

  3. Human Herpesviruses

    1. Herpes simplex virus DNA structure

      1. Michael J. Wagner, William C. Summers
        Pages 11-26
    2. Transcription of the viral DAN

      1. J. Barklie Clements, Andrew J. Easton, Frazer J. Rixon
        Pages 27-44
      2. Edward K. Wagner, Kevin P. Anderson, Robert E. Costa, Gayathri B. Davi, Beverley H. Gaylord, Louis E. Holland et al.
        Pages 45-67
    3. Replication of viral DNA

      1. Ivan Hirsch
        Pages 69-83
      2. Adam Friedmann, Samuel Rabkin, Yechiel Becker
        Pages 85-93
      3. Samuel Rabkin, Yehuda Shtram, Yechiel Becker
        Pages 95-106
    4. Defective viral DNA

      1. Dolores M. Cuifo, Gary S. Hayward
        Pages 107-128
      2. Niza Frenkel, Hilla Locker, Don Vlazny
        Pages 149-184
      3. Yechiel Becker, Samuel Rabkin
        Pages 185-195
    5. HSV DNA fragments in herpesvirus transformed cells

      1. Jeffrey M. Leiden, Niza Frenkel
        Pages 197-221
      2. G. Darby, K. F. Bastow, A. C. Minson
        Pages 223-253
      3. G. S. Hayward, G. R. Reyes, E. R. Gavis, S. L. Mcknight
        Pages 271-306
    6. Epstein-Barr virus

      1. K. Yamamoto, F. Mizuno, T. Matsuo, A. Tanaka, M. Nonoyama, T. Osato
        Pages 307-324
    7. Cytomegalovirus

      1. J. L. M. C. Geelen, M. W. Weststrate
        Pages 325-343
  4. Animal Herpesviruses

    1. G. Darai, R. M. Flügel, B. Matz, H. Delius
      Pages 345-361
    2. Tamar Ben-Porat, Albert S. Kaplan
      Pages 363-386
    3. Dennis J. O’Callaghan, Berch E. Henry, Joe H. Wharton, Steven A. Dauenhauer, Ralph B. Vance, John Staczek et al.
      Pages 387-418
  5. Back Matter
    Pages 463-466

About this book


Herpesviruses, classified in the family Herpesviridae, are important human and animal pathogens that can cause primary, latent or recurrent infections and even cancer. The major interest in research on herpesviruses today focuses on understanding the organization of the DNA genome, as well as on characterizing the viral genes in regard to their control and function. Modern techniques have allowed the viral DNA to become a molecular tool in the study of gene function, since it is now possible to implant the DNA into eukaryotic cells. This book contains original studies on the structure and organization of the DNA of human and animal herpes­ viruses. The various chapters acquaint the reader with the organization of the viral DNA, the mRNA transcripts, the replicative intermediates of the viral DNA, defective DNA genomes and their mode of synthesis, analyses of the viral DNA sequences in transformed cells, and the relationship between the presence of viral DNA fragments in the cancer cells and the transformed state of the cells.


Chromosom DNA electron microscopy genes microscopy transcription

Editors and affiliations

  • Yechiel Becker
    • 1
  1. 1.The Hebrew University of JerusalemJerusalemIsrael

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1981
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-015-6899-9
  • Online ISBN 978-94-015-6897-5
  • Buy this book on publisher's site