New Trends and Developments in Vaccines

  • A. Voller
  • H. Friedman

Table of contents

  1. Front Matter
    Pages i-x
  2. H. Friedman, A. Voller
    Pages 1-5
  3. W. Hennessen
    Pages 7-17
  4. S. A. Plotkin
    Pages 19-27
  5. Erling Norrby
    Pages 55-61
  6. C. Hannoun
    Pages 63-69
  7. J. Crick
    Pages 87-101
  8. C. Huygelen
    Pages 103-115
  9. J. Salk, D. Salk
    Pages 117-153
  10. M. R. Hilleman, V. M. Villarejos, E. B. Buynak, O. L. Ittensohn, W. J. McAleer, A. A. McLean et al.
    Pages 155-169
  11. A. J. Zuckerman
    Pages 171-177
  12. S. K. Vernon, W. C. Lawrence, Carole A. Long, G. H. Cohen, B. A. Rubin
    Pages 179-210
  13. T. K. Eisenstein
    Pages 211-222
  14. H. Friedman
    Pages 223-235
  15. W. A. Hankins
    Pages 245-253
  16. R. Triau
    Pages 255-273
  17. T. Lehner, S. J. Challacombe, Jill Caldwell
    Pages 275-298
  18. A. J. Beale
    Pages 311-314
  19. Back Matter
    Pages 321-323

About this book


It was not too long ago that many physicians and biomedical scientists felt that the era of 'vaccines' for protecting mankind against infectious disease was coming to an end. During the 1 940s and 50s the widespread use of newly developed antibiotics and antimicrobial chemotherapeutic agents suggested a new era in medicine, i. e. the control and eventual elimination of all infectious diseases, at least those caused by bacteria, by' chemical means. The magic 'bullet' proposed by Paul Ehrlich in the early 1900s seemed to be the method of choice for controling infection. However, it is now quite evident that those high expectations were unwarranted. Although many acute infections, especially those caused by pyogenic cocci, have been controlled by antibiotics, it is quite evident that infectious diseases, even those caused by bacteria, still are a major problem. Thus, the old 'standby' of preventative vaccination is making a strong comeback, not only for viral but also for bacterial infections. However, except for a relatively small number of viral diseases and those bacterial diseases due to toxin elaborated by microorganisms rather than invasion and replication of the microbe per se, preventative vaccination still has not fulfilled the expectations of their proponents. There has been a recent resurgence of interest concerning all aspects of vaccines, not only their preparation and administration, but also the nature and mechanism of the host immune response to the constituent micro­ organisms and their products.


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Editors and affiliations

  • A. Voller
    • 1
  • H. Friedman
    • 2
  1. 1.Nuffield Laboratories of Comparative Medicine, Institute of ZoologyZoological Society of LondonUK
  2. 2.Department of MicrobiologyAlbert Einstein Medical CenterNew YorkUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1978
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-011-6632-4
  • Online ISBN 978-94-011-6630-0
  • Buy this book on publisher's site