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Antigen Absorption by the Gut

  • W. A. Hemmings

Table of contents

  1. Front Matter
    Pages i-ix
  2. W. A. Hemmings
    Pages 1-2
  3. A. J. Husband, M. R. Brandon, A. K. Lascelles
    Pages 93-107
  4. A. L. Patey
    Pages 161-166
  5. A. M. Denman, T. Platts-Mills, P. J. Brereton, L. Doddymead, R. Soan, B. K. Pelton et al.
    Pages 167-181
  6. F. H. Y. Green, D. L. J. Freed
    Pages 189-197
  7. J. F. Woodley, E. E. Sterchi
    Pages 199-205
  8. J. L. Gowans
    Pages 219-222
  9. Back Matter
    Pages 223-226

About this book

Introduction

w. A. HEMMINGS The concept that proteins can enter cells whole is a difficult one. Yet the model situations whereby this process may be studied have been known and investigated for many years. Those situations arise through the specialization required to transfer immunoglobulins synthesized by the mother to the circulation of the fetus or newborn animal, that is in the transmission of passive immunity to the young. This always entails the protein crossing a continuous cellular barrier, in the placenta or fetal membranes, or in the intestinal epithelium. The concept is hard to accept in terms of cell biology because it is difficult to envisage a mechanism whereby proteins can pass in quantity a cell membrane which is regulating the entry of solutes. Brambell has put forward an hypothesis of such a mechanism, restating it in 'The transmission of passive immunity from mother to young' in 1970. In 1974, after his death, a symposium was held in Bangor largely on this subject, published as 'Maternofetal Transmission of Immunoglobulins' . Since then two further meetings have been held on gut transfer under the title of the present volume, which is composed of papers drawn from these two meetings.

Keywords

antigen

Editors and affiliations

  • W. A. Hemmings
    • 1
  1. 1.Agricultural Research Council, Immunology Group Zoology DepartmentUniversity College of North WalesBangorUSA

Bibliographic information

  • DOI https://doi.org/10.1007/978-94-011-6609-6
  • Copyright Information Springer Science+Business Media B.V. 1978
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-011-6611-9
  • Online ISBN 978-94-011-6609-6
  • Buy this book on publisher's site