Selected Topics in Mass Spectrometry in the Biomolecular Sciences

  • Richard M. Caprioli
  • Antonio Malorni
  • Giovanni Sindona

Part of the NATO ASI Series book series (ASIC, volume 504)

Table of contents

  1. Front Matter
    Pages i-xxvi
  2. Methods in Mass Spectrometry

    1. Front Matter
      Pages 1-1
    2. Simon J. Gaskell, Mark S. Bolgar, Isabel Riba, Scott G. Summerfield
      Pages 3-16
    3. Terry B. Farmer, Richard M. Caprioli
      Pages 55-84
    4. İ. T. Özgen, O. Altungöz, B. Salih, B. G. M. Vandeginste
      Pages 121-127
  3. Instrumentation for Mass Analysis and Detection

    1. Front Matter
      Pages 181-181
    2. O. V. Nemirovskiy, J. K. Gooden, R. Ramanathan, M. L. Gross
      Pages 183-211
    3. R. Graham Cooks, Guodong Chen, Carsten Weil
      Pages 213-238
    4. Marvin L. Vestal
      Pages 239-262
    5. Peter Kofel, Urs P. Schlunegger
      Pages 263-286
    6. Michael L. Easterling, I. Jonathan Amster
      Pages 287-314
  4. Application to Biomolecules

    1. Front Matter
      Pages 315-315
    2. D. Müller, P. Schindler, M. Coulot, W. J. Richter, W. Maerki, H. Grossenbacher
      Pages 317-345
    3. Margherita Ruoppolo, Fabio Talamo, Piero Pucci, Gennaro Marino
      Pages 347-359
    4. B. Spengler
      Pages 377-398
    5. Pasquale Ferranti, Nicola Sannolo, Gianfranco Mamone, Giuseppe Forte, Antonio Malorni
      Pages 399-411
    6. Virginia Carbone, Gabriella Pocsfalvi, Nicola Sannolo, Antonio Malorni
      Pages 413-425
    7. U. Bahr, M. Karas
      Pages 455-464
    8. H. Bartsch
      Pages 465-476
    9. D. Garozzo
      Pages 477-499
    10. Robert C. Murphy, Russell J. Waugh
      Pages 501-515
    11. Antonio De Nino, Anna Napoli, Giovanni Sindona
      Pages 517-531
  5. Back Matter
    Pages 581-586

About this book


Many fundamental aspects of the methods used in mass spectrometry are here presented by outstanding scientists, with reference to very recent developments. The principles and applications of electrospray, ion spray and MALDI ionization technique are presented, together with optimised GC/MS interfacing systems and tools for quantitative analysis. A comprehensive treatment of modern instrumentation for mass analysis and detection is also included. The major part of the book deals with bioanalytical applications to peptides, proteins, oligonucleotides, polysaccharides, lipids and plant metabolites. Several papers are devoted to the evaluation of adduct formation between DNA and carcinogens. Environmental applications are also included, with examples of some specific cases.
Fundamentals and applications are treated with the same degree of depth: the first two parts of the book therefore provide a basis for the understanding of the biomolecular applications section.
Audience: Ideal for advanced graduate students of chemistry who have learned some basic mass spectrometry. Also useful for Ph.D. students in chemistry, biology and medicine. Of value to researchers in academic and industrial laboratories.


DNA Lipid Mass Spectrometry Nucleotide Polysaccharid Termination proteins

Editors and affiliations

  • Richard M. Caprioli
    • 1
  • Antonio Malorni
    • 2
  • Giovanni Sindona
    • 3
  1. 1.Medical SchoolUniversity of TexasHoustonUSA
  2. 2.SESMA-C.N.R.NapoliItaly
  3. 3.Dipartimento di Chimica, Arcavacata di RendeUniversità della CalabriaItaly

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 1997
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-6171-1
  • Online ISBN 978-94-011-5165-8
  • Series Print ISSN 1389-2185
  • Buy this book on publisher's site