Structural Biology and Functional Genomics

  • E. Morton Bradbury
  • Sándor Pongor

Part of the NATO Science Series book series (ASHT, volume 71)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Paolo Catasti, Xian Chen, S. V. Santhana Mariappan, E. Morton Bradbury, Goutam Gupta
    Pages 19-51
  3. Alan Herbert, Alexander Rich
    Pages 53-72
  4. Jörg Langowski, Markus Hammermann, Konstantin Klenin, Katalin Tóth
    Pages 73-85
  5. T. R. Strick, D. Bensimon, V. Croquette
    Pages 87-96
  6. Kristian VlahoviČek, Mircea Gh. Munteanu, Sándor Pongor
    Pages 97-114
  7. Richard Lavery, Anne Lebrun
    Pages 115-131
  8. A. Simoncsits, M-L. Tjörnhammar, S. Wang, S. Pongor
    Pages 133-145
  9. David M. J. Lilley
    Pages 151-165
  10. Memmo Buttinelli, Gianna Panetta, Daniela Rhodes, Andrew Travers
    Pages 191-204
  11. Giuseppe Marzio, Mauro Giacca
    Pages 205-216
  12. A. I. Alexandrov, N. R. Cozzarelli, V. F. Holmes, A. B. Khodursky, B. J. Peter, L. Postow et al.
    Pages 217-233
  13. Thomas C. Terwilliger, Joel Berendzen
    Pages 235-249
  14. J. L. Sussman, E. E. Abola, D. Lin, J. Jiang, N. O. Manning, J. Prilusky
    Pages 251-264
  15. M. Y. Galperin, E. V. Koonin
    Pages 265-283
  16. F. Zanini, A. Lausi, A. Savoia
    Pages 285-301
  17. Back Matter
    Pages 303-313

About this book


Biomedical research will be revolutionised by the current efforts to sequence the human genome and the genomes of model organisms. Of the newly sequenced genes, 50% code for proteins of unknown functions, while as little as 5% of sequences in mammalian genomes code for proteins. New, genome-wide approaches are needed to draw together the knowledge that is emerging simultaneously in a number of fields of genome research.
This volume is a high-level survey of the newly emerging concepts of structural biology and functional genomics for biologists, biochemists and medical researchers interested in genome research. Topics included are chromosome and chromatin organisation, novel DNA and RNA structures, DNA flexibility, supercoiling, prediction of protein functions, strategies for large scale structural analysis, and computer modelling.


Chromosom DNA Expression biology enzymes gene expression genes protein proteins transcription

Editors and affiliations

  • E. Morton Bradbury
    • 1
  • Sándor Pongor
    • 2
  1. 1.Life Sciences DivisionLos Alamos National LaboratoryLos AlamosUSA
  2. 2.Agricultural Biotechnology CentreGödöllõHungary

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 1999
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-0-7923-5782-7
  • Online ISBN 978-94-011-4631-9
  • Series Print ISSN 1388-6576
  • Buy this book on publisher's site