Left Ventricular Hypertrophy

Physiology versus Pathology

  • Ernst E. Van der Wall
  • Arnoud Van der Laarse
  • Babette M. Pluim
  • Albert V. G. Bruschke

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 223)

Table of contents

  1. Front Matter
    Pages i-x
  2. A. van der Laarse, C. Ruwhof, J. E. T. van Wamel, E. E. van der Wall, A. V. G. Bruschke
    Pages 1-13
  3. R. A. Tio, R. de Boer, D. J. van Veldhuisen, W. H. van Gilst
    Pages 15-20
  4. A. J. Brees, B. M. Pluim, H. W. Vliegen, A. de Roos, H. J. Lamb, E. E. van der Wall
    Pages 43-53
  5. J. J. Schipperheijn
    Pages 55-64
  6. B. M. Pluim, A. van der Laarse, H. W. Vliegen, A. V. G. Bruschke, E. E. van der Wall
    Pages 65-84
  7. B. M. Pluim, A. van der Laarse, E. E. van der Wall
    Pages 85-106
  8. A. A. M. Wilde
    Pages 121-129
  9. A. van der Laarse, E. E. van der Wall
    Pages 131-138
  10. L. H. B. Baur, J. Braun, A. P. Kappetein, C. H. Peels, X. Y. Jin, Y. Houdas et al.
    Pages 139-150
  11. J. M. van Dantzig, R. Bronsaer, P. A. F. M. Doevendans
    Pages 151-161
  12. Back Matter
    Pages 175-182

About this book


The importance of left ventricular hypertrophy in cardiovascular disease has gained wide recognition. Left ventricular hypertrophy is a highly important risk factor associated with major cardiovascular events, including symptomatic heart failure, particularly in patients with systemic hypertension. Over the past years much has been learned about the genetics, molecular background, prevalence, incidence and prognosis of left ventricular hypertrophy. A variety of noninvasive methods has emerged for detecting left ventricular hypertrophy and the assessment of reversal of hypertrophy. Yet, a lot of controversy remains about the connotations and clinical implications of left ventricular hypertrophy. For instance, in the athlete's heart left ventricular hypertrophy may constitute a physiological adaptation to pressure overload, which normalizes following discontinuation of strenuous physical activity. On the other hand, in particular in patients with hypertension, left ventricular hypertrophy denotes a serious prognosis in the course of hypertension. In these patients left ventricular hypertrophy should be regarded as a grave prognostic sign rather than an innocent compensatory phenomenon. The distinction between physiologic and pathophysiologic left ventricular hypertrophy has been the basis for this book.


cardiovascular echocardiography electrocardiography genetics heart hypertension vascular disease

Authors and affiliations

  • Ernst E. Van der Wall
    • 1
  • Arnoud Van der Laarse
    • 1
  • Babette M. Pluim
    • 1
  • Albert V. G. Bruschke
    • 1
  1. 1.Leiden University Medical CenterLeidenThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Kluwer Academic Publishers 1999
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-010-5855-1
  • Online ISBN 978-94-011-4279-3
  • Series Print ISSN 0166-9842
  • Buy this book on publisher's site