Neurotox ’91

Molecular Basis of Drug & Pesticide Action

  • I. R. Duce

Table of contents

  1. Front Matter
    Pages i-xxvii
  2. Natural Products

    1. Front Matter
      Pages 1-1
    2. Gary Chiles, Seok-Ki Choi, Amira Eldefrawi, Mohyee Eldefrawi, Shinji Fushiya, Robert Goodnow Jr et al.
      Pages 3-17
    3. L. G. Magazanik, S. M. Antonov, V. Yu. Bolshakov, I. M. Fedorova, S. A. Gapon
      Pages 19-31
    4. Michael E. Adams, Vytautas P. Bindokas, Virginia J. Venema
      Pages 33-44
    5. Baldomero M. Olivera, Lourdes J. Cruz, Richard A. Myers, David R. Hillyard, Jean Rivier, Jamie K. Scott
      Pages 45-55
    6. J. M. Schaeffer, S. P. Rohrer, D. Cully, J. Arena
      Pages 71-76
  3. Molecular and Cellular Physiology of Insects and Nematodes

    1. Front Matter
      Pages 77-77
    2. R. J. Walker, L. M. Colquhoun, H. R. Parri, R. G. Williams, L. Holden-Dye
      Pages 105-121
    3. Michael O’Shea, Richard C. Rayne
      Pages 139-151
  4. Applications of Molecular Biology

    1. Front Matter
      Pages 153-153
    2. James A. Lewis, John T. Fleming, David Bird
      Pages 155-164
    3. Julian F. Burke, Kerris Bright, Susan E. Saunders, Elaine Kellett, Paul R. Benjamin
      Pages 179-190
    4. Linda A. King, Allan E. Atkinson, Louis A. Obosi, Isabel Bermudez, David J. Beadle
      Pages 191-202
    5. David B. Sattelle, Sarah C. R. Lummis, Howard A. Riina, John T. Fleming, Nicola M. Anthony, John Marshall
      Pages 203-219
  5. Molecular Structure

    1. Front Matter
      Pages 221-221
    2. Gordon C. K. Roberts
      Pages 223-239
    3. David J. Osguthorpe, George G. Luni, Victor B. Cockcroft
      Pages 241-253
  6. Resistance Mechanisms

    1. Front Matter
      Pages 255-255
    2. Young-Joon Ahn, Eisuke Funaki, Naoki Motoyama
      Pages 257-269
    3. Douglas C. Knipple, Kevin E. Doyle, Joseph E. Henderson, David M. Soderlund
      Pages 271-283
  7. Neuronal Networks and Behaviour

    1. Front Matter
      Pages 293-293
    2. Ronald M. Harris-Warrick, Robert E. Flamm, Bruce R. Johnson, Paul S. Katz, Ole Kiehn, Bing Zhang
      Pages 305-321
    3. John G. Hildebrand, Thomas A. Christensen, Edmund A. Arbas, Jon H. Hayashi, Uwe Homberg, Ryohei Kanzaki et al.
      Pages 323-338
    4. John A. Pickett, Lester J. Wadhams, Christine M. Woodcock
      Pages 339-348
  8. Back Matter
    Pages 349-362

About this book


NEUROTOX '91 was the fourth meeting in a series which started in 1979. The '91 meeting, like its predecessors, was held under the patronage of the Society of Chemical Industry, and despite the unfortunate proximity of hostilities in the Arabian Gulf attracted a truly international mix of industrial and academic pesticide scientists. This volume contains the text of invited papers read at the meeting and presents the dramatic developments which so excited those who attended. The potential of molecular neurobiology for gaining knowledge of target sites for neurotoxicants is now starting to be realised. These studies, in conjunction with developments in molecular imaging and modelling, provide new oppor­ tunities for chemists and biologists to gain insights into molecular interactions underlying intoxication. Molecular techniques have also enabled rapid ad­ vances on a second front, where the cloning of genes controlling pesticide resistance should have a profound impact on our understanding of this commercially important problem. The understanding of molecular events will undoubtedly be vital in future developments in chemical control of pests; however, the value of understand­ ing the way in which the nervous system controls behaviour and how behaviour can be modified by chemicals of bath synthetic and natural origins was highlighted. Natural products and their synthetic analogues have continued to provide new and interesting molecules which are already proving their worth as tools for the neuroscientist and may offer leads for commercial synthesis.


Calcium Glutamat Nervous System natural product neural network pesticide physiology

Editors and affiliations

  • I. R. Duce
    • 1
  1. 1.Department of Life ScienceUniversity of NottinghamNottinghamUK

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1992
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-1-85166-746-8
  • Online ISBN 978-94-011-2898-8
  • Buy this book on publisher's site