Clinical Applications of Cardiovascular Drugs

  • Leonard S. Dreifus
  • Albert N. Brest

Part of the Developments in Cardiovascular Medicine book series (DICM, volume 5)

Table of contents

  1. Front Matter
    Pages i-ix
  2. Leonard S. Dreifus, Joel Morganroth
    Pages 1-45
  3. Paul E. Fenster, Frank I. Marcus
    Pages 46-68
  4. Robert J. Henning, Max Harry Weil
    Pages 69-94
  5. Robert Zelis, A. James Liedtke, Stephen F. Flaim
    Pages 95-135
  6. William W. Parmley, Kanu Chatterjee
    Pages 136-154
  7. Albert N. Brest, David T. Lowenthal
    Pages 155-167
  8. David T. Lowenthal, Albert N. Brest
    Pages 168-190
  9. Edward Genton
    Pages 191-230
  10. Back Matter
    Pages 259-261

About this book


During the past decade enormous progress has been made in the development of new cardiovascular drugs and in our understanding of the clinical pharma­ cology and the pharmacokinetics of old drugs. In addition, newer applications of older agents have emerged. For example, vasodilators such as nitroglycerin are now being employed in the treatment of congestive heart failure, and anti­ hypertensives such as bretylium are used in the management of ventricular arrhythmias. Individual chapters in this book focus on (1) the clinical pharmacology and pharmacokinetics of the individual drugs, and (2) the clinical applications of these drugs, with attention also to serum concentrations, pathophysiology, and drug interactions where appropriate. The contributors to this text have labored to provide the reader with a meaningful, practical update on the clinical uses and usefulness of cardioactive drugs. We are deeply grateful to each of them for their generous participation in this endeavor. LEONARD S. DREIFUS, M.D. ALBERT N. BREST, M.D. 1. ANTIARRHYTHMIC AGENTS LEONARD S. DREIFUS and JOEL MORGANROTH Ideally, the management of cardiac arrhythmias must be predicated on (1) complete elucidation of the genesis of the various rhythm disturbances, and (2) a full understanding of the pharmacologic action of individual antiarrhythmic agents. Only with this precise information does it become possible to administer a particular agent or agents specifically effective against a given arrhythmia.


cardiovascular drugs research

Editors and affiliations

  • Leonard S. Dreifus
    • 1
  • Albert N. Brest
    • 2
  1. 1.Jefferson Medical CollegeThe Lankenau HospitalPhiladelphiaUSA
  2. 2.Jefferson Medical CollegePhiladelphiaUSA

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1980
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-90-247-2369-0
  • Online ISBN 978-94-010-9178-7
  • Series Print ISSN 0166-9842
  • Buy this book on publisher's site