Current and Future Immunosuppressive Therapies Following Transplantation

  • Mohamed H. Sayegh
  • Giuseppe Remuzzi

Table of contents

  1. Front Matter
    Pages i-ix
  2. Introduction

    1. Front Matter
      Pages 1-1
    2. Johnny C. Hong, Barry D. Kahan
      Pages 3-17
    3. P. Schnuelle, F. J. van der Woude
      Pages 19-40
  3. Pharmacological Immunosuppression

    1. Front Matter
      Pages 41-41
    2. Flavio Gaspari, Norberto Perico, Giuseppe Remuzzi
      Pages 43-59
    3. Donald E. Hricik
      Pages 61-84
    4. John D. Pirsch, Elias David-Neto
      Pages 85-110
    5. Venkataraman Ramanathan, J. Harold Helderman
      Pages 111-121
    6. Ron Shapiro
      Pages 123-142
    7. Barry D. Kahan
      Pages 143-163
    8. Jochen Klupp, Randall E. Morris
      Pages 165-183
  4. Biologicals

    1. Front Matter
      Pages 185-185
    2. John Vella, John Neylan
      Pages 187-204
    3. Paul Morrissey, Anthony P. Monaco
      Pages 205-220
    4. Flavio G. Vincenti
      Pages 235-248
    5. Markus H. Frank, David M. Briscoe
      Pages 249-263
    6. Roy D. Bloom, Laurence A. Turka
      Pages 265-277
    7. Barbara Murphy, Alan Krensky
      Pages 279-292
    8. Markus H. Frank, Mohamed H. Sayegh
      Pages 293-313
  5. Gene therapy

    1. Front Matter
      Pages 315-315
    2. Ariela Benigni, Norberto Perico, Giuseppe Remuzzi
      Pages 317-334
    3. John C. Magee, Randall S. Sung, Jonathan S. Bromberg
      Pages 335-356
    4. Ian P. J. Alwayn, Leo Bühler, Murali Basker, David K. C. Cooper
      Pages 357-388

About this book


This title provides a comprehensive and state-of-the-art summary of current and future immunosuppressive strategies in transplantation, with emphasis on the basic science mechanisms and clinical applicability of these strategies. The uniqueness of this book is the inclusion of up-to-date information on the basic mechanisms of actions of the immunosuppressive drugs as well as a summary of the clinical trials data and the potential use of these drugs in clinical organ transplantation. In addition to describing the various immunosuppressive strategies, the book has three special features, including immunosuppression in xenotransplantation, gene therapy approaches, and transplantation tolerance. A group of outstanding investigators have been assembled to write the chapters. The book is intended for the transplant professional and the specialist who wants to stay abreast of the current status of immunosuppression in organ transplantation. The book is also useful for basic scientists who work in the field of transplantation immunology.


T cell clinical trial gene therapy immunology immunosuppression kidney organ organ transplantation transplantation

Editors and affiliations

  • Mohamed H. Sayegh
    • 1
  • Giuseppe Remuzzi
    • 2
  1. 1.Harvard Medical SchoolBostonUSA
  2. 2.Mario Negri Institute for Pharmacological ResearchBergamoItaly

Bibliographic information