The Sinus Node

Structure, Function, and Clinical Relevance

  • Felix I. M. Bonke

Table of contents

  1. Front Matter
    Pages I-XII
  2. Function and Dysfunction of the Sinus Node

    1. Front Matter
      Pages 1-1
    2. Ludger Seipel, Guenter Breithardt, Christian Leuner
      Pages 36-45
    3. Harold C. Strauss, Melvin M. Scheinman, An LaBarre, David J. Browning, David G. Benditt, Andrew G. Wallace
      Pages 56-64
    4. Berndt Lüderitz, Gerhard Steinbeck, Christoph Naumann d’Alnoncourt, Werner Rosenberger
      Pages 77-88
    5. Harold C. Strauss, Melvin M. Scheinman, An LaBarre, David J. Browning, Thomas L. Wenger, Andrew G. Wallace
      Pages 103-111
    6. Onkar S. Narula, Miguel Vasquez, Narasimhan Shantha, Reuben Chuquimia, William D. Towne, Joseph W. Linhart
      Pages 112-128
    7. Günter Breithardt, Ludger Seipel, Eberhard Wiebringhaus
      Pages 129-138
    8. Kenneth M. Rosen, Ramesh C. Dhingra, Pablo Denes, Delon Wu, Christopher Wyndham, Fernando Amat-y-Leon
      Pages 139-146
  3. Relation Between Structure and Function of the Sinus Node

    1. Front Matter
      Pages 147-147
    2. J. Tranum-Jensen
      Pages 149-165
    3. Robert H. Anderson, Ho Siew Yen, Anton E. Becker, John A. Gosling
      Pages 166-182
    4. Michiel J. Janse, Jorgen Tranum-Jensen, André G. Kléber, Frans J.L. van Capelle
      Pages 183-194
    5. Mireille Masson-Pévet, W.K. Bleeker, A.J.C. Mackaay, D. Gros, L.N. Bouman
      Pages 195-211
    6. Anton E. Becker
      Pages 212-222
  4. Electrophysiology of the Sinus Node

  5. On the Mechanism of Pacemaking in the Sinus Node

  6. Does the Sinus Node Play a Role in Reentrant Arrhythmias?

    1. Front Matter
      Pages 377-377
    2. Anthony N. Damato
      Pages 379-388
    3. Günter Breithardt, Ludger Seipel
      Pages 389-408
    4. Hein J. J. Wellens
      Pages 428-428
  7. Back Matter
    Pages 429-459

About this book


For the clinician the sinus node is more or less a hidden structure and only by indirect assessment he is able to say something about the function of this center of pacemaker activity. The morphologist, however, is able to describe the structural microscopic and even electronmicroscopic features of this structure. The only disadvantage is that, as soon as he is coming into the picture, the tissue is dead. The physiologist tries to investigate the electrophysiological behavior of the sinus node. Since there is not a human being willing to give his sinus node for research, he has to do his investigation on isolated preparations of animals. Though there are a lot of experts in the field of the sinus node they nearly never speak the same 'language'. Therefore, it was my dream to bring all those people - or at least some of them -together on a workshop. I had the feeling that it was important to organize such a meeting without an audience but only with 'experts'.


arrhythmia drugs electrophysiology heart pacemaker physiology stroke

Editors and affiliations

  • Felix I. M. Bonke
    • 1
  1. 1.Dept. of Physiology, Biomedical CenterUniversity of LimburgMaastrichtThe Netherlands

Bibliographic information

  • DOI
  • Copyright Information Springer Science+Business Media B.V. 1978
  • Publisher Name Springer, Dordrecht
  • eBook Packages Springer Book Archive
  • Print ISBN 978-94-009-9717-2
  • Online ISBN 978-94-009-9715-8
  • Buy this book on publisher's site